Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACNI24_RS11380 Genome accession   NZ_CP182355
Coordinates   2275590..2277443 (+) Length   617 a.a.
NCBI ID   WP_419773983.1    Uniprot ID   -
Organism   MAG: Halarcobacter sp. isolate PCE-3     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2270590..2282443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNI24_RS11355 (ACNI24_11355) - 2272241..2272720 (+) 480 WP_258239003.1 J domain-containing protein -
  ACNI24_RS11360 (ACNI24_11360) - 2272737..2273234 (+) 498 WP_417327573.1 SprT-like domain-containing protein -
  ACNI24_RS11365 (ACNI24_11365) - 2273365..2273841 (+) 477 WP_417324969.1 glutathione peroxidase -
  ACNI24_RS11370 (ACNI24_11370) - 2273842..2274531 (+) 690 WP_419773982.1 phosphotransferase -
  ACNI24_RS11375 (ACNI24_11375) - 2274594..2275526 (+) 933 WP_417324786.1 hypothetical protein -
  ACNI24_RS11380 (ACNI24_11380) uvrC 2275590..2277443 (+) 1854 WP_419773983.1 excinuclease ABC subunit UvrC Machinery gene
  ACNI24_RS11385 (ACNI24_11385) - 2277447..2278469 (+) 1023 WP_419773984.1 alanine racemase -
  ACNI24_RS11390 (ACNI24_11390) - 2278480..2279145 (+) 666 WP_417324780.1 tetratricopeptide repeat protein -
  ACNI24_RS11395 (ACNI24_11395) - 2279150..2280121 (-) 972 WP_417327569.1 zinc transporter ZntB -
  ACNI24_RS11400 (ACNI24_11400) - 2280173..2280883 (-) 711 WP_417324776.1 2OG-Fe(II) oxygenase -
  ACNI24_RS11405 (ACNI24_11405) - 2281003..2281767 (-) 765 WP_419773985.1 competence/damage-inducible protein A -
  ACNI24_RS11410 (ACNI24_11410) - 2281770..2282354 (-) 585 WP_419773986.1 adenylate kinase -

Sequence

Protein


Download         Length: 617 a.a.        Molecular weight: 72117.33 Da        Isoelectric Point: 8.6811

>NTDB_id=1101364 ACNI24_RS11380 WP_419773983.1 2275590..2277443(+) (uvrC) [MAG: Halarcobacter sp. isolate PCE-3]
MNLEEKLKQLPNEAGVYQYFDKDGHLLYIGKAKVLKNRVKSYFKFTPNLQPAEKLGPRIYKMITEVVSLEWIVVPNEHEA
LILENSLIKQLKPKYNILLRDDKTYPYIMLDNSELFPRLEITRRVHKNNNIKYFGPYSTGARDMLDSIYEIVPLVQKKSC
IKGKEACLFHQIKKCHAPCEGKITTSDYAKLVDEACEYIYNKNKLINKLSERMMQYSEEFRFEEAMKLRDRIKSIEKSQI
KSGIDLASNEDLDLFAIKAGRKKGVVVRMFIRDGKLASSSHDFIKLDFLEDNKDIDLNEAYQRAIINYYNNEIPLLPKEI
LVAQELEEKEEIEEFLKERFDRNIKVVNPKKDKKKSLLNIALNNCDELLRIESSKNQITIYEEIKELFNLQTLPYIIESF
DNSHMMGQATVGAMVVWNEELNAFDKKQFRHYNLESKDEYSQMREMLMRRVESFEKVSPPDLWVIDGGETLLKLAYDIIQ
SAAVNLDIVAIAKEKVDAKAHRAKGAAKDIVHYKDKSGEIRSLKLKPSDQRLQFIQRQRDEAHRFVINFHKKQKRKEDKQ
VSLLQIKGIGEAKVKKLLLYFGSFEKIKEASVSELKEVLNEKDAILLNNYFHDEKED

Nucleotide


Download         Length: 1854 bp        

>NTDB_id=1101364 ACNI24_RS11380 WP_419773983.1 2275590..2277443(+) (uvrC) [MAG: Halarcobacter sp. isolate PCE-3]
ATGAATTTAGAAGAAAAACTAAAACAACTCCCTAACGAAGCAGGAGTTTATCAATACTTTGATAAAGATGGACACCTACT
TTATATTGGTAAAGCAAAAGTTCTTAAAAATAGAGTAAAATCTTACTTTAAATTTACACCTAATTTACAGCCAGCAGAAA
AACTTGGTCCTCGTATTTATAAGATGATTACAGAAGTTGTTTCTTTAGAGTGGATAGTTGTACCAAATGAACATGAAGCT
CTTATTTTAGAGAACTCACTTATTAAACAACTAAAACCTAAATACAATATTCTTTTACGAGATGATAAAACTTACCCATA
TATTATGTTAGATAATAGTGAACTTTTTCCTAGACTTGAAATAACAAGAAGAGTACATAAAAACAATAATATAAAATACT
TTGGTCCCTACTCAACAGGTGCTAGAGATATGCTTGATTCAATCTATGAAATAGTTCCTTTAGTTCAAAAGAAATCTTGT
ATCAAGGGTAAAGAAGCTTGTCTTTTCCATCAAATCAAAAAATGTCATGCCCCTTGTGAAGGGAAAATTACAACATCTGA
TTATGCAAAGCTAGTTGATGAAGCTTGTGAATATATCTATAATAAAAACAAATTAATCAATAAACTTAGTGAAAGAATGA
TGCAATACTCAGAAGAGTTTAGATTTGAAGAAGCGATGAAATTAAGAGATAGAATAAAATCAATCGAAAAATCTCAAATC
AAATCGGGTATTGATTTAGCTTCAAATGAAGACTTAGACCTTTTTGCAATAAAAGCTGGTAGAAAAAAAGGTGTTGTGGT
AAGAATGTTTATTAGAGATGGAAAACTTGCTTCTTCTTCCCATGACTTTATCAAACTTGACTTCTTAGAAGACAATAAAG
ATATTGATTTAAACGAGGCTTACCAAAGAGCAATTATCAATTACTATAATAATGAAATTCCTCTACTTCCCAAAGAGATT
TTAGTAGCTCAAGAGTTAGAAGAAAAAGAAGAGATAGAAGAGTTTTTAAAAGAGAGATTTGATAGAAATATAAAAGTTGT
AAATCCTAAAAAAGATAAGAAAAAATCTTTATTGAATATTGCACTAAATAACTGCGATGAACTACTTAGAATAGAATCTT
CTAAAAACCAAATAACTATATATGAAGAGATAAAAGAGCTATTTAACTTACAAACTCTTCCATATATAATAGAGAGTTTT
GATAACTCACATATGATGGGACAAGCTACAGTTGGAGCTATGGTTGTTTGGAATGAAGAACTTAATGCCTTTGATAAAAA
ACAGTTTAGACACTATAACTTAGAATCAAAAGATGAATACTCTCAAATGAGAGAAATGCTTATGCGAAGAGTTGAAAGCT
TTGAAAAAGTAAGTCCTCCTGACCTTTGGGTTATTGATGGAGGAGAAACTTTACTAAAACTTGCCTATGACATTATACAG
TCTGCTGCTGTAAACCTTGATATTGTAGCAATTGCTAAAGAAAAAGTAGATGCAAAAGCTCATAGGGCTAAAGGTGCTGC
AAAAGATATTGTTCACTATAAAGATAAAAGTGGTGAAATTAGAAGCTTAAAACTAAAACCTAGTGACCAAAGGTTACAAT
TTATACAAAGACAAAGGGATGAAGCCCACAGATTTGTTATAAACTTTCATAAGAAACAAAAAAGAAAAGAAGATAAACAA
GTTTCACTATTACAAATAAAAGGTATTGGTGAAGCAAAGGTTAAAAAACTACTTTTATATTTTGGAAGTTTTGAAAAAAT
AAAAGAAGCATCAGTATCAGAACTAAAAGAAGTTCTAAATGAAAAAGATGCTATTTTACTTAATAATTATTTCCATGATG
AAAAGGAAGATTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(14-96)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-547)

UvrB/uvrC motif (UVR)

(204-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

49.751

97.731

0.486

Multiple sequence alignment