Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACNI3G_RS10015 Genome accession   NZ_CP182346
Coordinates   2070568..2072400 (+) Length   610 a.a.
NCBI ID   WP_099312601.1    Uniprot ID   A0A347TJD8
Organism   MAG: Malaciobacter marinus isolate LRMN2-2     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2065568..2077400
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNI3G_RS09980 (ACNI3G_09980) - 2066316..2066621 (+) 306 WP_228150938.1 J domain-containing protein -
  ACNI3G_RS09985 (ACNI3G_09985) - 2066625..2067125 (+) 501 WP_129502415.1 SprT-like domain-containing protein -
  ACNI3G_RS09990 (ACNI3G_09990) - 2067122..2067757 (-) 636 WP_419782319.1 hypothetical protein -
  ACNI3G_RS09995 (ACNI3G_09995) - 2067768..2068046 (-) 279 WP_099312575.1 putative quinol monooxygenase -
  ACNI3G_RS10000 (ACNI3G_10000) pnuC 2068189..2068773 (+) 585 WP_419783095.1 nicotinamide riboside transporter PnuC -
  ACNI3G_RS10005 (ACNI3G_10005) - 2068832..2069524 (+) 693 WP_419782320.1 choline/ethanolamine kinase family protein -
  ACNI3G_RS10010 (ACNI3G_10010) - 2069623..2070531 (+) 909 WP_419777650.1 hypothetical protein -
  ACNI3G_RS10015 (ACNI3G_10015) uvrC 2070568..2072400 (+) 1833 WP_099312601.1 excinuclease ABC subunit UvrC Machinery gene
  ACNI3G_RS10020 (ACNI3G_10020) - 2072411..2073433 (+) 1023 WP_099312600.1 alanine racemase -
  ACNI3G_RS10025 (ACNI3G_10025) - 2073430..2074098 (+) 669 WP_419782321.1 tetratricopeptide repeat protein -
  ACNI3G_RS10030 (ACNI3G_10030) - 2074101..2074880 (-) 780 WP_228256087.1 molybdopterin-binding protein -
  ACNI3G_RS10035 (ACNI3G_10035) - 2074896..2075465 (-) 570 WP_099312596.1 adenylate kinase -
  ACNI3G_RS10040 (ACNI3G_10040) - 2075547..2077304 (-) 1758 WP_099312594.1 YgiQ family radical SAM protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 71361.84 Da        Isoelectric Point: 9.4996

>NTDB_id=1101309 ACNI3G_RS10015 WP_099312601.1 2070568..2072400(+) (uvrC) [MAG: Malaciobacter marinus isolate LRMN2-2]
MNLEEKLKELPNSAGVYQYFNKDGHLLYIGKAKVLKNRVKSYFKFTPNLAPADKLSPRIYKMITEVKSLEWIIAPNEHDA
LILENSLIKQLKPKYNILLRDDKTYPYIVIDYKEDFPRLEITRKVLKDKNIKYFGPYSTGARDMLDSIYEIIPLVQKKSC
IKGKEACLFHQIKKCYAPCVGKISKEEYSKIVDEALEYIYNKNKLIKKLNERMLQYSEEFRFEEAMKIRDRIKTIEKSQI
HTGMDLASNDNLDLFAIKASKEKAVIVRMFFRDGKLASSNHDYLKINQKELDIDLNEAYKRAIINYYDNEIPLLPKEIVV
ADEITQEIEELQEFIKDRFEKNIPIIHPKRGKKTQIIKIAINNCNELLRLQNSNATTIYKQLQELLNLSYTPNRFECFDN
SHMMGQATVGAMITWEEKFIKADYRHYNLEAKDEYAQMKETLIRRVQSFEKNPAPDVWVIDGGETLLKLAIDIRNSVGVN
LDIIAIAKEKLDFKAHRAKGSAKDIIYFEENSNIKRVDLLPSDKRLQFIQRLRDEAHRFAISFHKKQKRKDDSKISLLQI
KGIGEAKVKKLLLYFGEFEKIKNASFDELKIVLNEKDASLLINYFKTLDN

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=1101309 ACNI3G_RS10015 WP_099312601.1 2070568..2072400(+) (uvrC) [MAG: Malaciobacter marinus isolate LRMN2-2]
ATGAACTTAGAAGAAAAACTTAAAGAATTACCAAATAGTGCTGGTGTTTATCAGTACTTTAATAAAGATGGACACTTACT
TTATATAGGAAAAGCAAAGGTACTAAAAAATAGAGTTAAATCATATTTTAAATTTACTCCTAATTTAGCACCTGCTGATA
AATTAAGTCCTAGAATTTACAAAATGATAACTGAAGTGAAATCTTTAGAGTGGATTATTGCACCAAATGAACATGATGCA
CTTATACTTGAAAATTCACTTATTAAACAACTTAAACCAAAATACAATATTTTATTAAGAGATGATAAAACATATCCTTA
TATTGTTATTGATTATAAAGAAGATTTTCCAAGATTAGAAATAACAAGAAAAGTATTAAAAGATAAAAATATCAAATACT
TTGGTCCATATTCCACTGGTGCTAGAGATATGCTTGATAGTATTTATGAAATAATTCCTTTAGTACAAAAAAAATCTTGT
ATAAAAGGAAAAGAAGCTTGTCTTTTTCATCAAATAAAAAAATGCTATGCTCCTTGTGTTGGAAAAATTTCAAAAGAAGA
GTATAGTAAAATAGTTGATGAAGCCTTAGAATATATATACAATAAGAATAAATTAATTAAAAAATTAAATGAAAGAATGC
TTCAATACTCAGAAGAGTTTAGATTTGAAGAAGCTATGAAAATTAGAGATAGAATTAAAACAATTGAAAAATCTCAAATC
CATACGGGAATGGATTTAGCAAGTAATGATAATCTAGATTTATTTGCAATAAAAGCATCTAAAGAAAAAGCCGTAATAGT
AAGAATGTTTTTTAGAGATGGTAAGTTAGCTTCAAGTAACCATGATTATTTAAAAATAAATCAAAAAGAGCTTGACATAG
ACCTAAATGAAGCATATAAAAGAGCAATAATTAACTATTATGACAATGAAATTCCTTTACTACCAAAAGAGATAGTTGTA
GCTGATGAGATAACACAAGAAATTGAAGAGCTTCAAGAGTTTATAAAAGATAGATTTGAAAAAAATATTCCAATTATTCA
TCCAAAAAGAGGGAAGAAAACACAAATTATAAAAATTGCGATAAATAACTGTAATGAGCTTTTAAGACTTCAAAATAGTA
ATGCAACTACTATTTATAAACAACTACAAGAGTTATTAAACCTTTCATATACACCAAATAGATTTGAATGCTTTGATAAC
TCACATATGATGGGTCAAGCAACAGTTGGCGCAATGATTACTTGGGAAGAGAAGTTTATAAAAGCAGATTATAGACATTA
TAATCTTGAAGCAAAAGATGAATATGCACAAATGAAAGAAACACTAATAAGAAGAGTACAAAGTTTTGAAAAAAATCCAG
CTCCTGATGTTTGGGTTATTGATGGAGGAGAAACTTTATTAAAACTTGCTATTGATATAAGAAACTCTGTGGGAGTAAAT
CTTGATATAATTGCAATTGCAAAAGAAAAACTTGATTTTAAAGCACATAGAGCAAAAGGAAGTGCAAAAGATATAATCTA
TTTTGAAGAAAATAGTAATATAAAAAGAGTTGATTTACTTCCAAGTGATAAAAGATTACAATTTATTCAAAGACTAAGAG
ATGAAGCACATAGATTTGCAATCTCTTTTCATAAAAAACAAAAAAGAAAAGATGATAGTAAAATATCTTTACTTCAAATA
AAAGGAATTGGTGAAGCTAAAGTCAAAAAACTTCTTTTATATTTTGGAGAATTTGAAAAAATAAAAAATGCATCTTTTGA
TGAACTAAAAATTGTTTTAAATGAAAAGGATGCTTCATTATTAATAAACTATTTTAAAACATTAGATAACTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(383-541)

GIY-YIG catalytic domain (GIY-YIG)

(15-96)

UvrB/uvrC motif (UVR)

(204-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A347TJD8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

51.003

98.033

0.5

Multiple sequence alignment