Detailed information NTG0110055

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: HW00_RS13780
• Genome accession: NZ_CP008867
• Coordinates: 3005275..3008073 (+)
• Length: 932 a.a.
• NCBI ID: WP_003099937.1
• Uniprot ID: -
• Organism: Pseudomonas aeruginosa strain T52373
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3000275..3013073

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HW00_RS13760 (HW00_13780)	dbpA	3000757..3002133 (-)	1377	WP_025324554.1	ATP-dependent RNA helicase DbpA	-
HW00_RS13765 (HW00_13785)	-	3002481..3002690 (+)	210	WP_003084710.1	cold-shock protein	-
HW00_RS13770 (HW00_13790)	-	3002841..3003365 (+)	525	WP_003117916.1	ATP-dependent zinc protease	-
HW00_RS13775 (HW00_13795)	mdtD	3003468..3004901 (-)	1434	WP_025324553.1	multidrug transporter subunit MdtD	-
HW00_RS13780 (HW00_13800)	clpC	3005275..3008073 (+)	2799	WP_003099937.1	AAA family protein disaggregase ClpG	Regulator
HW00_RS13785 (HW00_13805)	-	3008175..3008753 (+)	579	WP_003084725.1	DUF2780 domain-containing protein	-
HW00_RS13790 (HW00_13810)	-	3009072..3009959 (-)	888	WP_003084727.1	acyltransferase	-
HW00_RS13795 (HW00_13815)	-	3010102..3010611 (+)	510	WP_003084733.1	ATP-dependent zinc protease	-
HW00_RS13800 (HW00_13820)	creB	3010696..3011385 (+)	690	WP_003084734.1	two-component system response regulator CreB	-
HW00_RS13805 (HW00_13825)	creC	3011385..3012809 (+)	1425	WP_059317167.1	two-component system sensor histidine kinase CreC	-

Sequence

Protein

• Length: 932 a.a.
• Molecular weight: 103439.97 Da
• Isoelectric Point: 6.8717

>NTDB_id=110055 HW00_RS13780 WP_003099937.1 3005275..3008073(+) (clpC) [Pseudomonas aeruginosa strain T52373]
MAQELCAICHERPAVARVSLVQNGQRRELALCELHYRQLMRQQRMRSPLESLFGGGSPFDEIFSGFGEQSPVTPVRAREP
EAVDIAEYFSKQTTEYLQRAAQVAAEFGKREVDTEHLLYALADADVVQAVLKQFGLSPADLKQYIEANAVRGASKGEASE
DMTISPRVKSALQHAFALSRELGHSYVGPEHLLLGLAAVPDSFAGTLLKKYGLTEQALRQKAVKVVGKGAEDGRVDGPSN
TPQLDKFSRDLTRLAREGKLDPVIGRSKEVETTIEVLARRKKNNPVLIGEPGVGKTAIVEGLAQRMVQGEVPEVLRDKRL
VELNINAMVAGAKYRGEFEERLKQVMDELQAAQSEIILFIDEVHTIVGAGQGGGEGGLDVANVLKPAMARGEMNLIGATT
LNEYQKYIEKDAALERRFQPVFVPEPTVEQTISILRGLRDKLEGHHKVTIRDEAFVAAAELSDRYIGNRFLPDKAIDLID
QAAARVRIASTSRPAEIQELEAELAQLKREQDYAASRKWYDEAKVFEKRIQERKEHLEQITERWQQTQGSKTEEVRVEDI
AEIISRLTGIPVTELTAEEREKLLQMEERLHQRVIGQQEAITAVSDAVRLARAGLRQGSRPIATFLFLGPTGVGKTELAK
ALAEVVFGDEDAMIRIDMSEYMERHAVSRLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHADVNNILLQVFDD
GRLTDGKGRVVDFTNTIIIATSNLGSELIMKNAQAGEFAQPPEKLKRELMTTLRGHFRPEFLNRLDEVIVFESLSKAQIE
DIVRLQLERVKRAAHAQDIYLHIDDSLVGHLAEEAYQPEFGARELKRQIRQQLETRLATAMLKGEVKEGETVTFFYDAKD
GVGYRKGTAPKPAARKKSGAGETPKGRATAARKPAAKKGAAAKGKADKPKAK

Nucleotide

• Length: 2799 bp

>NTDB_id=110055 HW00_RS13780 WP_003099937.1 3005275..3008073(+) (clpC) [Pseudomonas aeruginosa strain T52373]
ATGGCCCAGGAACTTTGCGCTATCTGCCACGAACGTCCCGCCGTCGCCCGCGTCAGCCTGGTACAGAACGGCCAGCGCCG
CGAACTCGCCCTCTGCGAACTGCACTACCGCCAGTTGATGCGCCAGCAGCGCATGCGCTCGCCGCTGGAGTCGCTGTTCG
GCGGCGGCAGCCCGTTCGACGAGATCTTCTCCGGCTTCGGCGAGCAGAGCCCGGTCACCCCGGTGCGCGCCCGCGAGCCG
GAGGCGGTGGACATCGCCGAGTACTTCAGCAAGCAGACCACCGAGTACCTGCAACGCGCCGCGCAGGTCGCCGCCGAATT
CGGCAAGCGCGAAGTGGACACCGAGCACCTGCTCTACGCCCTGGCCGACGCCGACGTGGTGCAGGCGGTGCTCAAGCAGT
TCGGCCTGTCGCCGGCCGACCTCAAGCAGTACATCGAGGCCAACGCCGTGCGCGGCGCCAGCAAGGGCGAGGCGAGCGAG
GACATGACCATCTCGCCGCGGGTGAAGAGCGCCTTGCAGCATGCCTTCGCCCTGTCCCGCGAACTCGGCCACAGCTATGT
CGGCCCCGAGCACCTGTTGCTCGGCCTGGCGGCGGTGCCGGACAGCTTCGCCGGGACGCTCCTGAAGAAGTACGGCCTGA
CCGAGCAGGCGCTACGGCAGAAAGCGGTCAAGGTGGTCGGCAAGGGCGCCGAGGACGGCCGCGTGGACGGCCCGAGCAAC
ACTCCGCAACTGGACAAGTTCAGCCGCGACCTGACCCGGCTGGCCCGCGAAGGCAAGCTCGATCCGGTGATCGGCCGCTC
GAAGGAAGTCGAGACCACCATCGAGGTTCTCGCCCGGCGCAAGAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCG
GCAAGACCGCCATCGTCGAAGGCCTGGCCCAGCGCATGGTCCAGGGCGAGGTGCCGGAGGTGCTGCGCGACAAGCGCCTG
GTCGAACTGAACATCAACGCCATGGTCGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAACGCCTCAAGCAGGTGATGGA
CGAACTGCAGGCGGCGCAGAGCGAGATCATCCTGTTCATCGACGAGGTGCACACCATCGTTGGTGCCGGCCAGGGCGGCG
GCGAAGGCGGGCTGGACGTGGCCAACGTGCTGAAGCCGGCGATGGCGCGTGGCGAGATGAACCTGATCGGCGCCACCACC
CTCAACGAGTACCAGAAGTACATCGAGAAGGACGCCGCGCTGGAGCGGCGCTTCCAGCCGGTGTTCGTCCCCGAGCCGAC
GGTGGAGCAGACCATCTCCATCCTCCGTGGCCTGCGCGACAAGCTCGAAGGCCACCACAAGGTGACCATCCGCGACGAGG
CCTTCGTCGCCGCCGCCGAGCTGTCCGATCGCTACATCGGCAACCGCTTCCTGCCGGACAAGGCCATCGACCTGATCGAC
CAGGCCGCCGCCCGCGTGCGCATCGCCAGCACCTCGCGGCCGGCCGAGATCCAGGAACTGGAGGCCGAGCTGGCGCAGCT
CAAGCGCGAGCAGGACTACGCCGCCAGCCGCAAGTGGTACGACGAGGCGAAGGTCTTCGAGAAACGCATCCAGGAACGCA
AGGAACACCTCGAGCAGATCACCGAGCGCTGGCAGCAGACCCAGGGGTCGAAGACCGAGGAGGTGCGGGTCGAGGACATC
GCCGAGATCATCTCCAGGCTCACCGGCATCCCGGTCACCGAACTGACCGCCGAGGAGCGCGAGAAGCTCCTGCAGATGGA
AGAGCGCCTGCACCAGCGGGTGATCGGCCAGCAGGAAGCGATCACCGCGGTCAGCGACGCCGTGCGCCTGGCCCGCGCCG
GGCTGCGCCAGGGCAGCCGGCCGATCGCCACCTTCCTGTTCCTCGGCCCGACCGGGGTGGGCAAGACCGAGCTGGCCAAG
GCCCTGGCCGAGGTGGTGTTCGGCGACGAAGACGCGATGATCCGCATCGACATGAGCGAATACATGGAGCGCCACGCGGT
GTCCCGGCTGATCGGTGCGCCGCCGGGCTACGTCGGCTACGACGAGGGCGGCCAGCTCACCGAGCGGGTGCGCCGGCGGC
CGTACAGCGTGATCCTGCTCGATGAGATCGAGAAGGCCCACGCCGACGTCAACAACATCCTCCTGCAGGTGTTCGACGAC
GGCCGCCTGACCGACGGCAAGGGGCGCGTGGTGGACTTCACCAATACCATCATCATCGCCACCAGCAACCTCGGCTCCGA
GCTGATCATGAAGAACGCCCAGGCCGGCGAGTTCGCCCAGCCGCCGGAGAAGCTCAAGCGCGAACTGATGACTACCCTGC
GCGGACATTTCCGCCCGGAATTCCTCAACCGCCTCGACGAGGTGATCGTCTTCGAGTCGCTGAGCAAGGCGCAGATCGAG
GACATCGTGCGCCTGCAACTGGAGCGGGTGAAGCGCGCCGCGCACGCTCAGGACATCTACCTGCACATCGACGACAGCCT
GGTCGGCCACCTCGCCGAAGAGGCCTACCAGCCGGAGTTCGGCGCCCGCGAGCTGAAGCGGCAGATCCGCCAGCAACTGG
AGACGCGCCTGGCCACGGCGATGCTCAAGGGCGAGGTGAAAGAGGGCGAGACGGTCACCTTCTTCTACGATGCCAAGGAC
GGCGTCGGCTACCGCAAGGGCACCGCGCCGAAGCCGGCGGCACGCAAGAAGTCCGGCGCCGGCGAGACGCCCAAGGGCCG
CGCGACGGCGGCGAGGAAGCCGGCGGCGAAGAAAGGCGCCGCCGCCAAGGGCAAGGCCGACAAGCCGAAGGCCAAGTGA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (100-147)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (175-226)

• AAA domain (Cdc48 subfamily) (AAA_2) (620-788)

• ATPase family associated with various cellular activities (AAA) (AAA) (286-419)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (794-873)

• AAA lid domain (AAA_lid_9) (427-524)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	50.247	86.91	0.437
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	45.113	85.622	0.386
clpC	Streptococcus thermophilus LMD-9	42.805	88.734	0.38
clpC	Streptococcus thermophilus LMG 18311	42.563	88.734	0.378
clpC	Streptococcus mutans UA159	41.383	88.412	0.366