Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   ACM67B_RS07280 Genome accession   NZ_CP181247
Coordinates   1522372..1524603 (-) Length   743 a.a.
NCBI ID   WP_416189072.1    Uniprot ID   -
Organism   Neisseria sp. CCUG17229     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 1517372..1529603
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM67B_RS07265 (ACM67B_07265) - 1519127..1519606 (-) 480 WP_416189069.1 FKBP-type peptidyl-prolyl cis-trans isomerase -
  ACM67B_RS07270 (ACM67B_07270) - 1520125..1520433 (+) 309 WP_416189070.1 hypothetical protein -
  ACM67B_RS07275 (ACM67B_07275) - 1520581..1521951 (+) 1371 WP_416189071.1 FAD-binding oxidoreductase -
  ACM67B_RS07280 (ACM67B_07280) comA 1522372..1524603 (-) 2232 WP_416189072.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACM67B_RS07285 (ACM67B_07285) cas2 1524885..1525211 (-) 327 WP_416189073.1 CRISPR-associated endonuclease Cas2 -
  ACM67B_RS07290 (ACM67B_07290) cas1 1525204..1526118 (-) 915 WP_416189074.1 type II CRISPR-associated endonuclease Cas1 -
  ACM67B_RS07295 (ACM67B_07295) cas9 1526191..1529462 (-) 3272 Protein_1412 type II CRISPR RNA-guided endonuclease Cas9 -

Sequence

Protein


Download         Length: 743 a.a.        Molecular weight: 81751.43 Da        Isoelectric Point: 9.6846

>NTDB_id=1099578 ACM67B_RS07280 WP_416189072.1 1522372..1524603(-) (comA) [Neisseria sp. CCUG17229]
MLRYVLPCWAFGVLVSFLLPVVPPLWAWIAVFGLILLAAWRWKPAAVLLCVLLGMAYGVWRTESALARQWPVARVENVAL
TMVVDDLPRRDERRVQFAAKAWDKDGGEYRLMLSDYQLRDWPVGSRWQVSARVRPVVGEVNLRGLNREAWALANGVGGMG
SLGKGRVLLAESGGLNLTLWRERISRNWQQANLYGHEFSDGIGLMRALGIGEQSALRAELWQAFRPLGLTHLVSISGLHV
TMVAVWFGFLVKLLLRALPVVPKRPRLWVLTGGVLGALLYAGLAGFGVPTQRSVLMLAAFAYAWWRGSGSSPWAGWWQAL
ALVLLFDPLAALGVGLWLSFGLVAALIWSSAGRLNERGWWLAVRGQWAVTLLSVVLLGYMFASLPLLSPLVNVVAIPWFS
WVLTPLALLGSALPFAPLQWLAAVLAEYTLRFLVWLAGYSPEFAVAAAPWPLMALAVLAALVLLLPRGTALKPWACLVLV
GFVFYRMQPLPEDRLKVWVWDAGQGLSVLMQTREHRLLFDTGTAYATGAGIVPSLNGLGIRRLDKLVLSHHDIDHDGGYT
AVKRSQPPQKLLAGQPEFYPQAEFCDESQWVWNGVVFEFLRPSEAYSGKDDNDESCVLRVVTDGQALLITGDMGQKGELD
LVQKYGDALYSQVLVLGHHGSNTASAGTFLNAVSPQYAVASSGYANSYGHPTKVVQNKVAAHGATLLRTDLSGALVFELG
GGAEVFQGRLKQQKFYWQKKPFD

Nucleotide


Download         Length: 2232 bp        

>NTDB_id=1099578 ACM67B_RS07280 WP_416189072.1 1522372..1524603(-) (comA) [Neisseria sp. CCUG17229]
ATGTTGCGTTATGTATTGCCGTGCTGGGCATTCGGGGTATTGGTGTCGTTCCTGTTGCCTGTGGTGCCGCCGTTGTGGGC
GTGGATTGCGGTGTTTGGGTTGATTTTATTGGCAGCTTGGCGTTGGAAACCGGCGGCAGTGTTGTTGTGTGTGTTGTTGG
GTATGGCTTATGGGGTGTGGCGTACGGAATCAGCGTTAGCGCGGCAATGGCCGGTGGCGCGGGTGGAGAATGTGGCGTTG
ACGATGGTAGTGGACGATTTGCCGCGCCGTGATGAGCGGCGGGTGCAGTTCGCGGCCAAGGCTTGGGATAAGGATGGCGG
CGAATATCGCTTGATGTTGTCGGATTATCAGTTGCGCGATTGGCCGGTGGGCAGCCGCTGGCAGGTGTCGGCGCGGGTGC
GGCCGGTGGTGGGTGAGGTGAACTTGCGCGGGCTCAATCGTGAGGCTTGGGCATTGGCCAATGGCGTGGGCGGCATGGGT
TCGTTGGGTAAGGGTAGGGTGTTGTTGGCGGAGTCGGGCGGCCTAAATTTGACGTTGTGGCGTGAACGCATCAGCCGCAA
TTGGCAGCAGGCGAATCTTTACGGACACGAGTTTTCAGACGGCATCGGTTTGATGCGGGCATTGGGTATTGGCGAACAAT
CGGCATTGCGGGCGGAATTGTGGCAGGCATTTCGGCCTTTGGGCTTAACGCATTTGGTGAGCATTTCGGGGCTGCATGTG
ACGATGGTGGCGGTGTGGTTCGGTTTTTTGGTGAAACTGTTGCTGCGGGCGCTGCCTGTGGTGCCGAAGCGGCCGAGATT
GTGGGTGTTGACGGGTGGTGTGCTGGGTGCGTTGTTGTATGCGGGTTTGGCGGGTTTTGGTGTGCCGACGCAGCGCAGTG
TGTTGATGTTGGCGGCGTTTGCTTATGCGTGGTGGCGCGGCAGCGGTTCATCGCCGTGGGCGGGCTGGTGGCAGGCTTTG
GCGCTGGTGTTGCTGTTTGATCCTTTGGCGGCATTGGGCGTGGGTTTGTGGCTGTCGTTTGGTTTGGTGGCGGCGCTGAT
TTGGTCGTCGGCAGGCCGTCTGAACGAACGCGGCTGGTGGCTGGCTGTGCGCGGGCAATGGGCGGTGACTTTGTTGTCGG
TGGTGTTGCTGGGCTATATGTTTGCTTCGCTGCCGCTGTTAAGCCCGCTGGTGAATGTGGTGGCGATTCCGTGGTTTTCT
TGGGTGTTGACGCCGCTGGCTTTACTCGGTTCGGCTCTGCCGTTTGCGCCGCTGCAATGGTTGGCGGCGGTGTTGGCGGA
ATACACGCTTCGGTTTTTGGTGTGGCTGGCAGGGTATTCGCCTGAATTTGCGGTGGCGGCTGCGCCTTGGCCGTTGATGG
CGTTGGCAGTTTTGGCGGCGTTGGTTTTACTGCTGCCACGCGGCACGGCTTTGAAACCTTGGGCTTGCTTGGTGCTGGTT
GGATTTGTGTTTTACCGTATGCAACCTTTGCCGGAAGACCGTCTGAAAGTGTGGGTATGGGATGCGGGGCAGGGTTTGTC
GGTATTGATGCAAACGCGCGAACACCGTTTGCTGTTCGATACAGGCACGGCATATGCGACAGGTGCGGGCATTGTACCAA
GCTTGAATGGGTTGGGCATTCGGCGGCTGGATAAGTTGGTGCTGTCGCATCATGACATTGATCACGACGGCGGCTATACG
GCAGTCAAGCGTAGTCAACCGCCGCAAAAGCTGCTAGCCGGACAGCCTGAATTTTATCCGCAAGCCGAGTTTTGTGACGA
ATCGCAATGGGTGTGGAATGGTGTGGTATTTGAGTTTCTCAGGCCGTCTGAAGCGTATTCGGGTAAAGATGACAACGATG
AAAGCTGTGTGTTACGTGTGGTGACCGACGGGCAGGCGCTGCTGATTACTGGCGATATGGGACAGAAGGGAGAACTGGAT
TTGGTGCAAAAATATGGTGATGCACTCTATAGCCAAGTATTGGTTTTGGGGCATCACGGCAGTAATACTGCCAGTGCGGG
CACGTTTTTGAATGCAGTGTCGCCGCAATATGCCGTAGCTTCAAGCGGCTATGCGAATAGCTACGGCCATCCGACCAAGG
TGGTGCAAAACAAAGTCGCGGCGCATGGGGCAACATTGTTGCGCACGGATTTATCAGGCGCGCTGGTGTTTGAGTTGGGT
GGTGGGGCGGAAGTTTTTCAAGGTCGTCTGAAACAGCAAAAGTTTTATTGGCAGAAAAAACCATTTGATTAA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(23-164)

Metallo-beta-lactamase superfamily (Lactamase_B)

(501-680)

Competence protein (Competence)

(209-465)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

67.341

99.731

0.672

Multiple sequence alignment