Detailed information NTG1099267

Bioinformatically predicted

Overview

• Name: agrA
• Type: Regulator
• Locus tag: ACM599_RS10400
• Genome accession: NZ_CP181152
• Coordinates: 2104196..2104912 (+)
• Length: 238 a.a.
• NCBI ID: WP_000688492.1
• Uniprot ID: A0A7U7IEW1
• Organism: Staphylococcus aureus strain AG21-0597
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2099196..2109912

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM599_RS10380 (ACM599_10380)	hld	2101783..2101863 (-)	81	WP_000046022.1	delta-hemolysin	-
ACM599_RS10385 (ACM599_10385)	-	2102153..2102716 (+)	564	WP_001105709.1	accessory gene regulator AgrB	-
ACM599_RS10390 (ACM599_10390)	agrD	2102720..2102860 (+)	141	WP_000735197.1	cyclic lactone autoinducer peptide AgrD	-
ACM599_RS10395 (ACM599_10395)	agrC	2102885..2104177 (+)	1293	WP_000387814.1	quorum-sensing sensor histidine kinase AgrC	-
ACM599_RS10400 (ACM599_10400)	agrA	2104196..2104912 (+)	717	WP_000688492.1	quorum-sensing response regulator AgrA	Regulator
ACM599_RS10405 (ACM599_10405)	-	2105286..2106245 (-)	960	WP_001253292.1	carbohydrate kinase family protein	-
ACM599_RS10410 (ACM599_10410)	-	2106242..2107726 (-)	1485	WP_001791588.1	sucrose-6-phosphate hydrolase	-
ACM599_RS10415 (ACM599_10415)	-	2107875..2108825 (-)	951	WP_000790325.1	LacI family DNA-binding transcriptional regulator	-

Sequence

Protein

• Length: 238 a.a.
• Molecular weight: 27905.90 Da
• Isoelectric Point: 6.0927

>NTDB_id=1099267 ACM599_RS10400 WP_000688492.1 2104196..2104912(+) (agrA) [Staphylococcus aureus strain AG21-0597]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide

• Length: 717 bp

>NTDB_id=1099267 ACM599_RS10400 WP_000688492.1 2104196..2104912(+) (agrA) [Staphylococcus aureus strain AG21-0597]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-120)

• LytTr DNA-binding domain (LytTR) (151-237)

3D structure

• AlphaFold DB: A0A7U7IEW1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
agrA	Staphylococcus aureus N315	100	100	1