Detailed information NTG1099229

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACM6AP_RS13165
• Genome accession: NZ_CP181151
• Coordinates: 2671084..2671971 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain AG21-0618
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2666084..2676971

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AP_RS13135 (ACM6AP_13135)	-	2666103..2666195 (+)	93	WP_010956583.1	hypothetical protein	-
ACM6AP_RS13140 (ACM6AP_13140)	-	2666303..2666800 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACM6AP_RS13145 (ACM6AP_13145)	-	2666810..2667070 (-)	261	WP_001791974.1	hypothetical protein	-
ACM6AP_RS13150 (ACM6AP_13150)	-	2667452..2667565 (-)	114	Protein_2550	hypothetical protein	-
ACM6AP_RS13155 (ACM6AP_13155)	-	2668224..2670224 (-)	2001	WP_000776750.1	ABC transporter permease	-
ACM6AP_RS13160 (ACM6AP_13160)	-	2670221..2670976 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACM6AP_RS13165 (ACM6AP_13165)	braS	2671084..2671971 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACM6AP_RS13170 (ACM6AP_13170)	braR	2671982..2672647 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACM6AP_RS13175 (ACM6AP_13175)	-	2672673..2672873 (-)	201	WP_000604730.1	hypothetical protein	-
ACM6AP_RS13180 (ACM6AP_13180)	-	2673071..2674495 (+)	1425	WP_000953755.1	alkaline phosphatase	-
ACM6AP_RS13185 (ACM6AP_13185)	-	2674555..2674656 (-)	102	WP_000731976.1	SE2200 family small protein	-
ACM6AP_RS13190 (ACM6AP_13190)	-	2674778..2675233 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACM6AP_RS13195 (ACM6AP_13195)	-	2675478..2676239 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1099229 ACM6AP_RS13165 WP_000143425.1 2671084..2671971(-) (braS) [Staphylococcus aureus strain AG21-0618]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1099229 ACM6AP_RS13165 WP_000143425.1 2671084..2671971(-) (braS) [Staphylococcus aureus strain AG21-0618]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1