Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACM6AP_RS10045 Genome accession   NZ_CP181151
Coordinates   2055407..2056123 (+) Length   238 a.a.
NCBI ID   WP_053865603.1    Uniprot ID   -
Organism   Staphylococcus aureus strain AG21-0618     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2050407..2061123
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM6AP_RS10015 (ACM6AP_10015) - 2050624..2051250 (+) 627 WP_000522381.1 nitroreductase family protein -
  ACM6AP_RS10020 (ACM6AP_10020) - 2051611..2052396 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  ACM6AP_RS10025 (ACM6AP_10025) hld 2052996..2053076 (-) 81 WP_000046022.1 delta-hemolysin -
  ACM6AP_RS10030 (ACM6AP_10030) - 2053366..2053929 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  ACM6AP_RS10035 (ACM6AP_10035) agrD 2053932..2054075 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  ACM6AP_RS10040 (ACM6AP_10040) agrC 2054105..2055388 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  ACM6AP_RS10045 (ACM6AP_10045) agrA 2055407..2056123 (+) 717 WP_053865603.1 quorum-sensing response regulator AgrA Regulator
  ACM6AP_RS10050 (ACM6AP_10050) - 2056195..2056304 (+) 110 Protein_1944 hypothetical protein -
  ACM6AP_RS10055 (ACM6AP_10055) - 2056492..2057451 (-) 960 WP_001253312.1 carbohydrate kinase family protein -
  ACM6AP_RS10060 (ACM6AP_10060) - 2057448..2058932 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  ACM6AP_RS10065 (ACM6AP_10065) - 2059081..2060031 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27953.99 Da        Isoelectric Point: 6.3001

>NTDB_id=1099225 ACM6AP_RS10045 WP_053865603.1 2055407..2056123(+) (agrA) [Staphylococcus aureus strain AG21-0618]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLYIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1099225 ACM6AP_RS10045 WP_053865603.1 2055407..2056123(+) (agrA) [Staphylococcus aureus strain AG21-0618]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTATATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment