Detailed information NTG1099187

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACM6AC_RS13420
• Genome accession: NZ_CP181150
• Coordinates: 2693271..2694158 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain AG21-0600
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2688271..2699158

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AC_RS13390 (ACM6AC_13390)	-	2688285..2688377 (+)	93	WP_010956583.1	hypothetical protein	-
ACM6AC_RS13395 (ACM6AC_13395)	-	2688485..2688982 (-)	498	WP_001065267.1	glutathione peroxidase	-
ACM6AC_RS13400 (ACM6AC_13400)	-	2688992..2689252 (-)	261	WP_209205822.1	hypothetical protein	-
ACM6AC_RS13405 (ACM6AC_13405)	-	2689634..2689747 (-)	114	WP_072468803.1	hypothetical protein	-
ACM6AC_RS13410 (ACM6AC_13410)	-	2690411..2692411 (-)	2001	WP_154283809.1	ABC transporter permease	-
ACM6AC_RS13415 (ACM6AC_13415)	-	2692408..2693163 (-)	756	WP_154283810.1	ABC transporter ATP-binding protein	-
ACM6AC_RS13420 (ACM6AC_13420)	braS	2693271..2694158 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACM6AC_RS13425 (ACM6AC_13425)	braR	2694169..2694834 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACM6AC_RS13430 (ACM6AC_13430)	-	2694860..2695060 (-)	201	WP_154283811.1	hypothetical protein	-
ACM6AC_RS13435 (ACM6AC_13435)	-	2695258..2696682 (+)	1425	WP_416152413.1	alkaline phosphatase	-
ACM6AC_RS13440 (ACM6AC_13440)	-	2696742..2696843 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACM6AC_RS13445 (ACM6AC_13445)	-	2696965..2697420 (-)	456	WP_416152414.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACM6AC_RS13450 (ACM6AC_13450)	-	2697665..2698426 (-)	762	WP_154283812.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1099187 ACM6AC_RS13420 WP_000143420.1 2693271..2694158(-) (braS) [Staphylococcus aureus strain AG21-0600]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1099187 ACM6AC_RS13420 WP_000143420.1 2693271..2694158(-) (braS) [Staphylococcus aureus strain AG21-0600]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGTTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAGGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993