Detailed information NTG1099181

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACM6AC_RS09505
• Genome accession: NZ_CP181150
• Coordinates: 1942039..1943082 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AG21-0600
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1937039..1948082

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AC_RS09475 (ACM6AC_09475)	-	1937457..1938713 (-)	1257	WP_001793428.1	aminopeptidase	-
ACM6AC_RS09480 (ACM6AC_09480)	-	1938716..1938916 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACM6AC_RS09485 (ACM6AC_09485)	-	1939063..1939527 (+)	465	WP_154284135.1	low molecular weight protein-tyrosine-phosphatase	-
ACM6AC_RS09490 (ACM6AC_09490)	-	1939534..1939809 (+)	276	WP_154284136.1	YtxH domain-containing protein	-
ACM6AC_RS09495 (ACM6AC_09495)	-	1940087..1941304 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
ACM6AC_RS09500 (ACM6AC_09500)	vraR	1941420..1942049 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACM6AC_RS09505 (ACM6AC_09505)	vraS	1942039..1943082 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACM6AC_RS09510 (ACM6AC_09510)	liaF	1943079..1943780 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACM6AC_RS09515 (ACM6AC_09515)	-	1943795..1944181 (-)	387	WP_001110179.1	hypothetical protein	-
ACM6AC_RS09520 (ACM6AC_09520)	map	1944398..1945156 (-)	759	WP_000636144.1	type I methionyl aminopeptidase	-
ACM6AC_RS09525 (ACM6AC_09525)	-	1945623..1946609 (+)	987	WP_154284137.1	FUSC family protein	-
ACM6AC_RS09530 (ACM6AC_09530)	-	1947040..1947453 (-)	414	WP_154284138.1	hypothetical protein	-
ACM6AC_RS09535 (ACM6AC_09535)	-	1947482..1947592 (-)	111	WP_154284139.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1099181 ACM6AC_RS09505 WP_001017131.1 1942039..1943082(-) (vraS) [Staphylococcus aureus strain AG21-0600]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1099181 ACM6AC_RS09505 WP_001017131.1 1942039..1943082(-) (vraS) [Staphylococcus aureus strain AG21-0600]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTTTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTACGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1