Detailed information NTG1099146

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACM6AA_RS13420
• Genome accession: NZ_CP181149
• Coordinates: 2692416..2693303 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain AG21-0598
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2687416..2698303

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AA_RS13390 (ACM6AA_13390)	-	2687430..2687522 (+)	93	WP_010956583.1	hypothetical protein	-
ACM6AA_RS13395 (ACM6AA_13395)	-	2687630..2688127 (-)	498	WP_001065267.1	glutathione peroxidase	-
ACM6AA_RS13400 (ACM6AA_13400)	-	2688137..2688397 (-)	261	WP_209205822.1	hypothetical protein	-
ACM6AA_RS13405 (ACM6AA_13405)	-	2688779..2688892 (-)	114	WP_072468803.1	hypothetical protein	-
ACM6AA_RS13410 (ACM6AA_13410)	-	2689556..2691556 (-)	2001	WP_154283809.1	ABC transporter permease	-
ACM6AA_RS13415 (ACM6AA_13415)	-	2691553..2692308 (-)	756	WP_154283810.1	ABC transporter ATP-binding protein	-
ACM6AA_RS13420 (ACM6AA_13420)	braS	2692416..2693303 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACM6AA_RS13425 (ACM6AA_13425)	braR	2693314..2693979 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACM6AA_RS13430 (ACM6AA_13430)	-	2694005..2694205 (-)	201	WP_154283811.1	hypothetical protein	-
ACM6AA_RS13435 (ACM6AA_13435)	-	2694403..2695827 (+)	1425	WP_416152413.1	alkaline phosphatase	-
ACM6AA_RS13440 (ACM6AA_13440)	-	2695887..2695988 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACM6AA_RS13445 (ACM6AA_13445)	-	2696110..2696565 (-)	456	WP_416152414.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACM6AA_RS13450 (ACM6AA_13450)	-	2696810..2697571 (-)	762	WP_154283812.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1099146 ACM6AA_RS13420 WP_000143420.1 2692416..2693303(-) (braS) [Staphylococcus aureus strain AG21-0598]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1099146 ACM6AA_RS13420 WP_000143420.1 2692416..2693303(-) (braS) [Staphylococcus aureus strain AG21-0598]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGTTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAGGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993