Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACM6AA_RS10235 Genome accession   NZ_CP181149
Coordinates   2061788..2062504 (+) Length   238 a.a.
NCBI ID   WP_209206015.1    Uniprot ID   -
Organism   Staphylococcus aureus strain AG21-0598     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2056788..2067504
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM6AA_RS10205 (ACM6AA_10205) - 2057004..2057630 (+) 627 WP_416152363.1 nitroreductase family protein -
  ACM6AA_RS10210 (ACM6AA_10210) - 2057991..2058776 (+) 786 WP_000867943.1 carbon-nitrogen family hydrolase -
  ACM6AA_RS10215 (ACM6AA_10215) hld 2059375..2059455 (-) 81 WP_000046022.1 delta-hemolysin -
  ACM6AA_RS10220 (ACM6AA_10220) - 2059745..2060308 (+) 564 WP_115289668.1 accessory gene regulator AgrB -
  ACM6AA_RS10225 (ACM6AA_10225) agrD 2060312..2060452 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  ACM6AA_RS10230 (ACM6AA_10230) agrC 2060477..2061769 (+) 1293 WP_000387809.1 quorum-sensing sensor histidine kinase AgrC -
  ACM6AA_RS10235 (ACM6AA_10235) agrA 2061788..2062504 (+) 717 WP_209206015.1 quorum-sensing response regulator AgrA Regulator
  ACM6AA_RS10240 (ACM6AA_10240) - 2062576..2062683 (+) 108 WP_154284415.1 hypothetical protein -
  ACM6AA_RS10245 (ACM6AA_10245) - 2062872..2063831 (-) 960 WP_154284416.1 carbohydrate kinase family protein -
  ACM6AA_RS10250 (ACM6AA_10250) - 2063828..2065312 (-) 1485 WP_154284417.1 sucrose-6-phosphate hydrolase -
  ACM6AA_RS10255 (ACM6AA_10255) - 2065461..2066411 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27931.98 Da        Isoelectric Point: 6.0927

>NTDB_id=1099142 ACM6AA_RS10235 WP_209206015.1 2061788..2062504(+) (agrA) [Staphylococcus aureus strain AG21-0598]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDLKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1099142 ACM6AA_RS10235 WP_209206015.1 2061788..2062504(+) (agrA) [Staphylococcus aureus strain AG21-0598]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATCCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACACGTATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCTCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTTGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment