Detailed information NTG1099063

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACM6AW_RS13295
• Genome accession: NZ_CP181145
• Coordinates: 2672081..2672968 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain AG21-0629
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2667081..2677968

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AW_RS13265 (ACM6AW_13265)	-	2667100..2667192 (+)	93	WP_010956583.1	hypothetical protein	-
ACM6AW_RS13270 (ACM6AW_13270)	-	2667300..2667797 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACM6AW_RS13275 (ACM6AW_13275)	-	2667807..2668067 (-)	261	WP_001791974.1	hypothetical protein	-
ACM6AW_RS13280 (ACM6AW_13280)	-	2668449..2668562 (-)	114	Protein_2576	hypothetical protein	-
ACM6AW_RS13285 (ACM6AW_13285)	-	2669221..2671221 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACM6AW_RS13290 (ACM6AW_13290)	-	2671218..2671973 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACM6AW_RS13295 (ACM6AW_13295)	braS	2672081..2672968 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACM6AW_RS13300 (ACM6AW_13300)	braR	2672979..2673644 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACM6AW_RS13305 (ACM6AW_13305)	-	2673670..2673870 (-)	201	WP_000604730.1	hypothetical protein	-
ACM6AW_RS13310 (ACM6AW_13310)	-	2674068..2675492 (+)	1425	WP_000953755.1	alkaline phosphatase	-
ACM6AW_RS13315 (ACM6AW_13315)	-	2675552..2675653 (-)	102	WP_000731976.1	SE2200 family small protein	-
ACM6AW_RS13320 (ACM6AW_13320)	-	2675775..2676230 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACM6AW_RS13325 (ACM6AW_13325)	-	2676475..2677236 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1099063 ACM6AW_RS13295 WP_000143425.1 2672081..2672968(-) (braS) [Staphylococcus aureus strain AG21-0629]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1099063 ACM6AW_RS13295 WP_000143425.1 2672081..2672968(-) (braS) [Staphylococcus aureus strain AG21-0629]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1