Detailed information NTG1099057

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACM6AW_RS09425
• Genome accession: NZ_CP181145
• Coordinates: 1933178..1934221 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AG21-0629
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1928178..1939221

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AW_RS09395 (ACM6AW_09395)	-	1928599..1929855 (-)	1257	WP_001795108.1	aminopeptidase	-
ACM6AW_RS09400 (ACM6AW_09400)	-	1929858..1930058 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACM6AW_RS09405 (ACM6AW_09405)	-	1930205..1930669 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACM6AW_RS09410 (ACM6AW_09410)	-	1930676..1930951 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACM6AW_RS09415 (ACM6AW_09415)	-	1931229..1932446 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
ACM6AW_RS09420 (ACM6AW_09420)	vraR	1932559..1933188 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACM6AW_RS09425 (ACM6AW_09425)	vraS	1933178..1934221 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACM6AW_RS09430 (ACM6AW_09430)	liaF	1934218..1934919 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACM6AW_RS09435 (ACM6AW_09435)	-	1934934..1935320 (-)	387	WP_001110179.1	hypothetical protein	-
ACM6AW_RS09440 (ACM6AW_09440)	map	1935537..1936295 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACM6AW_RS09445 (ACM6AW_09445)	-	1936826..1937812 (+)	987	WP_000999717.1	FUSC family protein	-
ACM6AW_RS09450 (ACM6AW_09450)	-	1938243..1938656 (-)	414	WP_001557448.1	hypothetical protein	-
ACM6AW_RS09455 (ACM6AW_09455)	-	1938685..1938795 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1099057 ACM6AW_RS09425 WP_001017131.1 1933178..1934221(-) (vraS) [Staphylococcus aureus strain AG21-0629]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1099057 ACM6AW_RS09425 WP_001017131.1 1933178..1934221(-) (vraS) [Staphylococcus aureus strain AG21-0629]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1