Detailed information NTG1099019

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACM6AX_RS13300
• Genome accession: NZ_CP181142
• Coordinates: 2673600..2674487 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain AG21-0630
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2668600..2679487

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AX_RS13270 (ACM6AX_13270)	-	2668619..2668711 (+)	93	WP_010956583.1	hypothetical protein	-
ACM6AX_RS13275 (ACM6AX_13275)	-	2668819..2669316 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACM6AX_RS13280 (ACM6AX_13280)	-	2669326..2669586 (-)	261	WP_001791974.1	hypothetical protein	-
ACM6AX_RS13285 (ACM6AX_13285)	-	2669968..2670081 (-)	114	Protein_2577	hypothetical protein	-
ACM6AX_RS13290 (ACM6AX_13290)	-	2670740..2672740 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACM6AX_RS13295 (ACM6AX_13295)	-	2672737..2673492 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACM6AX_RS13300 (ACM6AX_13300)	braS	2673600..2674487 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACM6AX_RS13305 (ACM6AX_13305)	braR	2674498..2675163 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACM6AX_RS13310 (ACM6AX_13310)	-	2675189..2675389 (-)	201	WP_000604730.1	hypothetical protein	-
ACM6AX_RS13315 (ACM6AX_13315)	-	2675587..2677011 (+)	1425	WP_000953755.1	alkaline phosphatase	-
ACM6AX_RS13320 (ACM6AX_13320)	-	2677071..2677172 (-)	102	WP_000731976.1	SE2200 family small protein	-
ACM6AX_RS13325 (ACM6AX_13325)	-	2677294..2677749 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACM6AX_RS13330 (ACM6AX_13330)	-	2677994..2678755 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1099019 ACM6AX_RS13300 WP_000143425.1 2673600..2674487(-) (braS) [Staphylococcus aureus strain AG21-0630]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1099019 ACM6AX_RS13300 WP_000143425.1 2673600..2674487(-) (braS) [Staphylococcus aureus strain AG21-0630]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1