Detailed information NTG1099013

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACM6AX_RS09430
• Genome accession: NZ_CP181142
• Coordinates: 1934698..1935741 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AG21-0630
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1929698..1940741

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AX_RS09400 (ACM6AX_09400)	-	1930119..1931375 (-)	1257	WP_001795108.1	aminopeptidase	-
ACM6AX_RS09405 (ACM6AX_09405)	-	1931378..1931578 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACM6AX_RS09410 (ACM6AX_09410)	-	1931725..1932189 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACM6AX_RS09415 (ACM6AX_09415)	-	1932196..1932471 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACM6AX_RS09420 (ACM6AX_09420)	-	1932749..1933966 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
ACM6AX_RS09425 (ACM6AX_09425)	vraR	1934079..1934708 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACM6AX_RS09430 (ACM6AX_09430)	vraS	1934698..1935741 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACM6AX_RS09435 (ACM6AX_09435)	liaF	1935738..1936439 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACM6AX_RS09440 (ACM6AX_09440)	-	1936454..1936840 (-)	387	WP_001110179.1	hypothetical protein	-
ACM6AX_RS09445 (ACM6AX_09445)	map	1937057..1937815 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACM6AX_RS09450 (ACM6AX_09450)	-	1938346..1939332 (+)	987	WP_000999717.1	FUSC family protein	-
ACM6AX_RS09455 (ACM6AX_09455)	-	1939763..1940176 (-)	414	WP_001557448.1	hypothetical protein	-
ACM6AX_RS09460 (ACM6AX_09460)	-	1940205..1940315 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1099013 ACM6AX_RS09430 WP_001017131.1 1934698..1935741(-) (vraS) [Staphylococcus aureus strain AG21-0630]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1099013 ACM6AX_RS09430 WP_001017131.1 1934698..1935741(-) (vraS) [Staphylococcus aureus strain AG21-0630]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1