Detailed information NTG1098969

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACM6AB_RS09910
• Genome accession: NZ_CP181140
• Coordinates: 2002865..2003908 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AG21-0599
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1997865..2008908

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AB_RS09880 (ACM6AB_09880)	-	1998286..1999542 (-)	1257	WP_001795108.1	aminopeptidase	-
ACM6AB_RS09885 (ACM6AB_09885)	-	1999545..1999745 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACM6AB_RS09890 (ACM6AB_09890)	-	1999892..2000356 (+)	465	WP_416152907.1	low molecular weight protein-tyrosine-phosphatase	-
ACM6AB_RS09895 (ACM6AB_09895)	-	2000363..2000638 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACM6AB_RS09900 (ACM6AB_09900)	-	2000916..2002133 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
ACM6AB_RS09905 (ACM6AB_09905)	vraR	2002246..2002875 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACM6AB_RS09910 (ACM6AB_09910)	vraS	2002865..2003908 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACM6AB_RS09915 (ACM6AB_09915)	liaF	2003905..2004606 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACM6AB_RS09920 (ACM6AB_09920)	-	2004621..2005007 (-)	387	WP_001110179.1	hypothetical protein	-
ACM6AB_RS09925 (ACM6AB_09925)	map	2005224..2005982 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACM6AB_RS09930 (ACM6AB_09930)	-	2006513..2007499 (+)	987	WP_000999717.1	FUSC family protein	-
ACM6AB_RS09935 (ACM6AB_09935)	-	2007930..2008343 (-)	414	WP_001557448.1	hypothetical protein	-
ACM6AB_RS09940 (ACM6AB_09940)	-	2008372..2008482 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1098969 ACM6AB_RS09910 WP_001017131.1 2002865..2003908(-) (vraS) [Staphylococcus aureus strain AG21-0599]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1098969 ACM6AB_RS09910 WP_001017131.1 2002865..2003908(-) (vraS) [Staphylococcus aureus strain AG21-0599]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1