Detailed information NTG1098838

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACM6EM_RS10080
• Genome accession: NZ_CP181134
• Coordinates: 2034754..2035797 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AG21-0594
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2029754..2040797

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6EM_RS10050 (ACM6EM_10050)	-	2030172..2031428 (-)	1257	WP_001795438.1	aminopeptidase	-
ACM6EM_RS10055 (ACM6EM_10055)	-	2031431..2031631 (-)	201	WP_000180461.1	DUF1128 family protein	-
ACM6EM_RS10060 (ACM6EM_10060)	-	2031778..2032242 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACM6EM_RS10065 (ACM6EM_10065)	-	2032249..2032524 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACM6EM_RS10070 (ACM6EM_10070)	-	2032802..2034019 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
ACM6EM_RS10075 (ACM6EM_10075)	vraR	2034135..2034764 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
ACM6EM_RS10080 (ACM6EM_10080)	vraS	2034754..2035797 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACM6EM_RS10085 (ACM6EM_10085)	liaF	2035794..2036495 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACM6EM_RS10090 (ACM6EM_10090)	-	2036510..2036896 (-)	387	WP_001110179.1	hypothetical protein	-
ACM6EM_RS10095 (ACM6EM_10095)	map	2037113..2037871 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACM6EM_RS10100 (ACM6EM_10100)	-	2038399..2039385 (+)	987	WP_000999713.1	FUSC family protein	-
ACM6EM_RS10105 (ACM6EM_10105)	-	2039875..2040288 (-)	414	WP_001549145.1	hypothetical protein	-
ACM6EM_RS10110 (ACM6EM_10110)	-	2040317..2040427 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1098838 ACM6EM_RS10080 WP_001017131.1 2034754..2035797(-) (vraS) [Staphylococcus aureus strain AG21-0594]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1098838 ACM6EM_RS10080 WP_001017131.1 2034754..2035797(-) (vraS) [Staphylococcus aureus strain AG21-0594]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1