Detailed information NTG1098717

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACM597_RS14010
• Genome accession: NZ_CP181126
• Coordinates: 2777024..2777911 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain AG21-0595
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2772024..2782911

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM597_RS13980 (ACM597_13980)	-	2772043..2772135 (+)	93	WP_010956583.1	hypothetical protein	-
ACM597_RS13985 (ACM597_13985)	-	2772243..2772740 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACM597_RS13990 (ACM597_13990)	-	2772750..2773010 (-)	261	WP_001789910.1	hypothetical protein	-
ACM597_RS13995 (ACM597_13995)	-	2773392..2773505 (-)	114	WP_001791776.1	hypothetical protein	-
ACM597_RS14000 (ACM597_14000)	-	2774164..2776164 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACM597_RS14005 (ACM597_14005)	-	2776161..2776916 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACM597_RS14010 (ACM597_14010)	braS	2777024..2777911 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACM597_RS14015 (ACM597_14015)	braR	2777922..2778587 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACM597_RS14020 (ACM597_14020)	-	2778613..2778813 (-)	201	WP_000604728.1	hypothetical protein	-
ACM597_RS14025 (ACM597_14025)	-	2779011..2780435 (+)	1425	WP_000953744.1	alkaline phosphatase	-
ACM597_RS14030 (ACM597_14030)	-	2780495..2780596 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACM597_RS14035 (ACM597_14035)	-	2780718..2781173 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACM597_RS14040 (ACM597_14040)	-	2781418..2782179 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1098717 ACM597_RS14010 WP_000143419.1 2777024..2777911(-) (braS) [Staphylococcus aureus strain AG21-0595]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1098717 ACM597_RS14010 WP_000143419.1 2777024..2777911(-) (braS) [Staphylococcus aureus strain AG21-0595]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997