Detailed information NTG1098669

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACM6AE_RS09730
• Genome accession: NZ_CP181124
• Coordinates: 1981106..1982149 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AG21-0604
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1976106..1987149

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AE_RS09700 (ACM6AE_09700)	-	1976527..1977783 (-)	1257	WP_001795108.1	aminopeptidase	-
ACM6AE_RS09705 (ACM6AE_09705)	-	1977786..1977986 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACM6AE_RS09710 (ACM6AE_09710)	-	1978133..1978597 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACM6AE_RS09715 (ACM6AE_09715)	-	1978604..1978879 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACM6AE_RS09720 (ACM6AE_09720)	-	1979157..1980374 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
ACM6AE_RS09725 (ACM6AE_09725)	vraR	1980487..1981116 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACM6AE_RS09730 (ACM6AE_09730)	vraS	1981106..1982149 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACM6AE_RS09735 (ACM6AE_09735)	liaF	1982146..1982847 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACM6AE_RS09740 (ACM6AE_09740)	-	1982862..1983248 (-)	387	WP_001110179.1	hypothetical protein	-
ACM6AE_RS09745 (ACM6AE_09745)	map	1983465..1984223 (-)	759	WP_000636140.1	type I methionyl aminopeptidase	-
ACM6AE_RS09750 (ACM6AE_09750)	-	1984754..1985740 (+)	987	WP_000999717.1	FUSC family protein	-
ACM6AE_RS09755 (ACM6AE_09755)	-	1986171..1986584 (-)	414	WP_001557448.1	hypothetical protein	-
ACM6AE_RS09760 (ACM6AE_09760)	-	1986613..1986723 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1098669 ACM6AE_RS09730 WP_001017131.1 1981106..1982149(-) (vraS) [Staphylococcus aureus strain AG21-0604]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1098669 ACM6AE_RS09730 WP_001017131.1 1981106..1982149(-) (vraS) [Staphylococcus aureus strain AG21-0604]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1