Detailed information NTG1098546

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACM6AH_RS14245
• Genome accession: NZ_CP181115
• Coordinates: 2796871..2797758 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain AG21-0608
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2791871..2802758

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AH_RS14215 (ACM6AH_14215)	-	2791890..2791982 (+)	93	WP_010956583.1	hypothetical protein	-
ACM6AH_RS14220 (ACM6AH_14220)	-	2792090..2792587 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACM6AH_RS14225 (ACM6AH_14225)	-	2792597..2792857 (-)	261	WP_001791974.1	hypothetical protein	-
ACM6AH_RS14230 (ACM6AH_14230)	-	2793239..2793352 (-)	114	Protein_2766	hypothetical protein	-
ACM6AH_RS14235 (ACM6AH_14235)	-	2794011..2796011 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACM6AH_RS14240 (ACM6AH_14240)	-	2796008..2796763 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACM6AH_RS14245 (ACM6AH_14245)	braS	2796871..2797758 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACM6AH_RS14250 (ACM6AH_14250)	braR	2797769..2798434 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACM6AH_RS14255 (ACM6AH_14255)	-	2798460..2798660 (-)	201	WP_000604730.1	hypothetical protein	-
ACM6AH_RS14260 (ACM6AH_14260)	-	2798858..2800282 (+)	1425	WP_000953755.1	alkaline phosphatase	-
ACM6AH_RS14265 (ACM6AH_14265)	-	2800342..2800443 (-)	102	WP_000731976.1	SE2200 family small protein	-
ACM6AH_RS14270 (ACM6AH_14270)	-	2800565..2801020 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACM6AH_RS14275 (ACM6AH_14275)	-	2801265..2802026 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1098546 ACM6AH_RS14245 WP_000143425.1 2796871..2797758(-) (braS) [Staphylococcus aureus strain AG21-0608]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1098546 ACM6AH_RS14245 WP_000143425.1 2796871..2797758(-) (braS) [Staphylococcus aureus strain AG21-0608]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1