Detailed information NTG1098500

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACM6AI_RS14290
• Genome accession: NZ_CP181113
• Coordinates: 2812353..2813240 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain AG21-0609
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2807353..2818240

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AI_RS14260 (ACM6AI_14260)	-	2807372..2807464 (+)	93	WP_010956583.1	hypothetical protein	-
ACM6AI_RS14265 (ACM6AI_14265)	-	2807572..2808069 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACM6AI_RS14270 (ACM6AI_14270)	-	2808079..2808339 (-)	261	WP_001791974.1	hypothetical protein	-
ACM6AI_RS14275 (ACM6AI_14275)	-	2808721..2808834 (-)	114	Protein_2772	hypothetical protein	-
ACM6AI_RS14280 (ACM6AI_14280)	-	2809493..2811493 (-)	2001	WP_000776750.1	ABC transporter permease	-
ACM6AI_RS14285 (ACM6AI_14285)	-	2811490..2812245 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACM6AI_RS14290 (ACM6AI_14290)	braS	2812353..2813240 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACM6AI_RS14295 (ACM6AI_14295)	braR	2813251..2813916 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACM6AI_RS14300 (ACM6AI_14300)	-	2813942..2814142 (-)	201	WP_000604730.1	hypothetical protein	-
ACM6AI_RS14305 (ACM6AI_14305)	-	2814340..2815764 (+)	1425	WP_000953755.1	alkaline phosphatase	-
ACM6AI_RS14310 (ACM6AI_14310)	-	2815824..2815925 (-)	102	WP_000731976.1	SE2200 family small protein	-
ACM6AI_RS14315 (ACM6AI_14315)	-	2816047..2816502 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACM6AI_RS14320 (ACM6AI_14320)	-	2816747..2817508 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1098500 ACM6AI_RS14290 WP_000143425.1 2812353..2813240(-) (braS) [Staphylococcus aureus strain AG21-0609]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1098500 ACM6AI_RS14290 WP_000143425.1 2812353..2813240(-) (braS) [Staphylococcus aureus strain AG21-0609]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1