Detailed information NTG1098451

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACM6AJ_RS10405
• Genome accession: NZ_CP181111
• Coordinates: 2073715..2074758 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AG21-0610
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2068715..2079758

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AJ_RS10375 (ACM6AJ_10375)	-	2069133..2070389 (-)	1257	WP_001795438.1	aminopeptidase	-
ACM6AJ_RS10380 (ACM6AJ_10380)	-	2070392..2070592 (-)	201	WP_000180461.1	DUF1128 family protein	-
ACM6AJ_RS10385 (ACM6AJ_10385)	-	2070739..2071203 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACM6AJ_RS10390 (ACM6AJ_10390)	-	2071210..2071485 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACM6AJ_RS10395 (ACM6AJ_10395)	-	2071763..2072980 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
ACM6AJ_RS10400 (ACM6AJ_10400)	vraR	2073096..2073725 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
ACM6AJ_RS10405 (ACM6AJ_10405)	vraS	2073715..2074758 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACM6AJ_RS10410 (ACM6AJ_10410)	liaF	2074755..2075456 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACM6AJ_RS10415 (ACM6AJ_10415)	-	2075471..2075857 (-)	387	WP_001110179.1	hypothetical protein	-
ACM6AJ_RS10420 (ACM6AJ_10420)	map	2076074..2076832 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACM6AJ_RS10425 (ACM6AJ_10425)	-	2077360..2078346 (+)	987	WP_000999713.1	FUSC family protein	-
ACM6AJ_RS10430 (ACM6AJ_10430)	-	2078836..2079249 (-)	414	WP_001549145.1	hypothetical protein	-
ACM6AJ_RS10435 (ACM6AJ_10435)	-	2079278..2079388 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1098451 ACM6AJ_RS10405 WP_001017131.1 2073715..2074758(-) (vraS) [Staphylococcus aureus strain AG21-0610]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1098451 ACM6AJ_RS10405 WP_001017131.1 2073715..2074758(-) (vraS) [Staphylococcus aureus strain AG21-0610]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1