Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACM6AU_RS09855 Genome accession   NZ_CP181097
Coordinates   1993593..1994309 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain AG21-0627     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1988593..1999309
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM6AU_RS09825 (ACM6AU_09825) - 1988809..1989435 (+) 627 WP_000522375.1 nitroreductase family protein -
  ACM6AU_RS09830 (ACM6AU_09830) - 1989796..1990581 (+) 786 WP_000867944.1 carbon-nitrogen family hydrolase -
  ACM6AU_RS09835 (ACM6AU_09835) hld 1991182..1991262 (-) 81 WP_000046022.1 delta-hemolysin -
  ACM6AU_RS09840 (ACM6AU_09840) agrB 1991551..1992120 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  ACM6AU_RS09845 (ACM6AU_09845) agrD 1992117..1992257 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ACM6AU_RS09850 (ACM6AU_09850) agrC 1992282..1993574 (+) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  ACM6AU_RS09855 (ACM6AU_09855) agrA 1993593..1994309 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ACM6AU_RS09860 (ACM6AU_09860) - 1994381..1994488 (+) 108 WP_031785433.1 hypothetical protein -
  ACM6AU_RS09865 (ACM6AU_09865) - 1994678..1995637 (-) 960 WP_001253295.1 carbohydrate kinase family protein -
  ACM6AU_RS09870 (ACM6AU_09870) - 1995634..1997118 (-) 1485 WP_000141419.1 sucrose-6-phosphate hydrolase -
  ACM6AU_RS09875 (ACM6AU_09875) - 1997267..1998217 (-) 951 WP_000790314.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1098193 ACM6AU_RS09855 WP_000688492.1 1993593..1994309(+) (agrA) [Staphylococcus aureus strain AG21-0627]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1098193 ACM6AU_RS09855 WP_000688492.1 1993593..1994309(+) (agrA) [Staphylococcus aureus strain AG21-0627]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAGGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment