Detailed information NTG1098191

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACM6AU_RS09120
• Genome accession: NZ_CP181097
• Coordinates: 1875084..1876127 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AG21-0627
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1870084..1881127

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM6AU_RS09090 (ACM6AU_09090)	-	1870505..1871752 (-)	1248	WP_000656302.1	aminopeptidase	-
ACM6AU_RS09095 (ACM6AU_09095)	-	1871764..1871964 (-)	201	WP_000180459.1	DUF1128 family protein	-
ACM6AU_RS09100 (ACM6AU_09100)	-	1872111..1872575 (+)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
ACM6AU_RS09105 (ACM6AU_09105)	-	1872582..1872857 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACM6AU_RS09110 (ACM6AU_09110)	-	1873135..1874352 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
ACM6AU_RS09115 (ACM6AU_09115)	vraR	1874465..1875094 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
ACM6AU_RS09120 (ACM6AU_09120)	vraS	1875084..1876127 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACM6AU_RS09125 (ACM6AU_09125)	liaF	1876124..1876825 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACM6AU_RS09130 (ACM6AU_09130)	-	1876840..1877226 (-)	387	WP_001110184.1	hypothetical protein	-
ACM6AU_RS09135 (ACM6AU_09135)	map	1877443..1878201 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
ACM6AU_RS09140 (ACM6AU_09140)	-	1878788..1879774 (+)	987	WP_000999713.1	FUSC family protein	-
ACM6AU_RS09145 (ACM6AU_09145)	-	1879952..1880365 (-)	414	WP_001622129.1	hypothetical protein	-
ACM6AU_RS09150 (ACM6AU_09150)	-	1880394..1880503 (-)	110	Protein_1765	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1098191 ACM6AU_RS09120 WP_001017131.1 1875084..1876127(-) (vraS) [Staphylococcus aureus strain AG21-0627]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1098191 ACM6AU_RS09120 WP_001017131.1 1875084..1876127(-) (vraS) [Staphylococcus aureus strain AG21-0627]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1