Detailed information NTG0109763

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ABXG87_RS00515
• Genome accession: NZ_AP031488
• Coordinates: 83992..86442 (+)
• Length: 816 a.a.
• NCBI ID: WP_041817177.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain NBRC 13956
• Function: degradation of ComX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	86429..87923	83992..86442	flank	-13

Gene organization within MGE regions

Location: 83992..87923

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABXG87_RS00515 (Ssa13956_00630)	clpC	83992..86442 (+)	2451	WP_041817177.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
ABXG87_RS00520	-	86429..87923 (-)	1495	Protein_65	IS1182-like element ISSth2 family transposase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90410.77 Da
• Isoelectric Point: 5.6275

>NTDB_id=109763 ABXG87_RS00515 WP_041817177.1 83992..86442(+) (clpC) [Streptococcus salivarius strain NBRC 13956]
MTTYSRKMQAIFHRAQLEAERFGSPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIRAEEIETAAVLAMEKSPKDLSESDI
IDLRAQSHALEVMLQEAEGIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERYAGLS
KQDLKAIHDLRKPKKSKASGNFANMMQPPQSSTGELSDYTKDLTAVAELDALDPVIGREKEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVPEAIDILKGLRSSYEDYHRVTI
TDEAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQGRIKKEAKREITPLDEALLSGDMKAAVKQYKASQKAKLPEPAL
VDADQIMQTLSRLSGIPVEKMTQADSKRYLNLEAELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTIGFGAQDISHNHQAMQSRIMEELKKAYRPEFINRIDEKVV
FHSLEEEQLREIVKIMMKPLVSALAEKGIDLKFQPAALKHLAKDGYDVEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=109763 ABXG87_RS00515 WP_041817177.1 83992..86442(+) (clpC) [Streptococcus salivarius strain NBRC 13956]
ATGACGACATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAGGCAGAGCGTTTTGGAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTCGCTATGGTTGAGGTTCCAGGATCTGTAGCCTACCTAACATTTACTGATTTTGAGGACC
GTATTCGTGCGGAAGAGATTGAGACCGCTGCTGTACTAGCGATGGAGAAAAGTCCAAAAGACTTGTCTGAATCAGATATT
ATCGATTTACGTGCACAGTCACATGCTTTAGAGGTTATGTTGCAAGAGGCAGAGGGAATTGCTAGTGTGACTGGTGCTGT
AGAGGTAGGGTCTGAACATGTATTGATGGCCTTCCTTCTTCATAAGGATTTGATGGTTTGTCGTCTCCTTGAAGTTGCTG
GTTTTCAATATAAGGATGACAGCGATAAGCCTCGTATTATCGATTTACGACGTTCTTTGGAGCGTTACGCAGGTCTTAGT
AAGCAAGATTTGAAGGCCATTCATGACCTTCGTAAGCCTAAAAAATCAAAGGCATCAGGAAATTTTGCTAATATGATGCA
GCCTCCTCAATCTTCTACTGGGGAACTGTCAGATTATACCAAAGACTTAACGGCAGTAGCCGAATTAGATGCTCTTGATC
CTGTTATTGGACGTGAGAAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAACCCAGTTCTTGTG
GGTGAAGCAGGTGTTGGTAAGACGGCACTTGCGCTTGGCTTAGCACAGCGTATTGCTTCAGGCGAAGTACCTTTTGAGTT
GGCTGATATGCGTATCTTAGAGCTTGATATGATGAGTGTGGTTGCAGGAACACGTTTCCGTGGCGATTTCGAAGAACGTA
TGAATCAGATCATTGATGAGATTGAAGCTGATGGAAAAATCATTCTTTTTATTGACGAATTGCATACGATTATTGGTTCT
GGTTCAGGTATTGATAGCACCTTAGATGCGGCGAATATTTTGAAACCCGCTCTAGCACGTGGAACTCTTCATATGGTTGG
AGCAACTACTCAAGCTGAGTACCAGAAGCATATTGAGAAAGATGCAGCTCTTTCTCGCCGTTTTGCTAAGATTACAATTG
AGGAGCCAAGTGTACCTGAGGCGATTGATATTCTAAAAGGCCTACGTTCGTCTTATGAAGACTATCATCGTGTAACGATT
ACTGATGAGGCGGTTGAGACAGCAGTCAAGGCAGCCCACCGTTATTTGACGAGTAAAAACTTGCCTGACTCTGCCATTGA
TCTTTTAGATGAAGCGAGTGCAACTGTTCAAGGTCGTATCAAAAAAGAAGCCAAACGTGAGATAACGCCTTTGGATGAAG
CGCTTCTATCTGGTGATATGAAGGCTGCTGTTAAACAATATAAAGCTAGCCAAAAAGCAAAATTACCAGAACCTGCCTTG
GTAGATGCAGATCAGATTATGCAAACCCTTAGTCGTCTATCAGGTATTCCTGTTGAGAAGATGACTCAGGCAGATAGCAA
GCGTTACTTGAATCTGGAAGCAGAGCTTCATAAACGTGTTATTGGTCAAGACGAAGCAGTTTCAGCGATTAGTCGTGCTA
TTCGTCGTAACCAGTCAGGTATTCGTACTGGAAAACGTCCGATTGGTTCCTTCATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAGTTGGCCAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAGTCAGCTTTGCTTCGCTTTGACATGTCAGAATA
CATGGAAAAATTTGCGGCTAGCCGCCTTAATGGTGCTCCTCCAGGTTATGTTGGATATGATGAGGGTGGTGAATTAACAG
AGAAAGTTCGCAATAAGCCTTACTCAGTTCTCCTCTTTGACGAGGTGGAAAAGGCTCACCCAGATATTTTCAACATCCTC
TTACAGGTTTTGGATGATGGTGTCTTGACGGATAGTCGAGGTCGTAAAGTCGATTTCTCAAATACCATTATCATTATGAC
TTCGAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACTATTGGATTTGGTGCCCAAGACATTTCTCATAATCACCAAG
CAATGCAGTCACGTATCATGGAAGAACTTAAGAAGGCCTACCGTCCAGAGTTTATCAACCGTATTGATGAGAAGGTTGTC
TTCCATAGTCTAGAGGAAGAGCAACTTCGTGAGATTGTCAAGATTATGATGAAACCGTTGGTATCAGCTTTGGCTGAAAA
AGGGATTGACTTGAAATTCCAACCAGCTGCTCTCAAGCATTTAGCTAAAGATGGCTATGATGTTGAGATGGGTGCTCGTC
CATTACGTCGCACGATTCAAACTCAAGTGGAGGACAAGTTATCTGAGCTCTTACTAGGTGGTCAAGTAGTTAGTGGACAA
ACTCTTAAAATCGGCTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (378-457)

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (108-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	94.73	100	0.947
clpC	Streptococcus thermophilus LMD-9	94.608	100	0.946
clpC	Streptococcus mutans UA159	72.549	100	0.725
clpC	Streptococcus pneumoniae TIGR4	66.912	100	0.669
clpC	Streptococcus pneumoniae Rx1	66.789	100	0.668
clpC	Streptococcus pneumoniae D39	66.789	100	0.668
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.421	100	0.513
clpC	Bacillus subtilis subsp. subtilis str. 168	47.509	100	0.479
clpE	Streptococcus mutans UA159	47.604	76.716	0.365