Detailed information NTG1097141

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ACL43R_RS01870
• Genome accession: NZ_CP180647
• Coordinates: 371452..373902 (+)
• Length: 816 a.a.
• NCBI ID: WP_185767512.1
• Uniprot ID: -
• Organism: Lactococcus formosensis strain JAL11
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 366452..378902

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACL43R_RS01845 (ACL43R_01845)	-	367376..367888 (+)	513	WP_003135164.1	adenine phosphoribosyltransferase	-
ACL43R_RS01850 (ACL43R_01850)	rpoE	368014..368574 (+)	561	WP_096368662.1	DNA-directed RNA polymerase subunit delta	-
ACL43R_RS01855 (ACL43R_01855)	mltG	368679..370391 (+)	1713	WP_416037652.1	endolytic transglycosylase MltG	-
ACL43R_RS01860 (ACL43R_01860)	greA	370417..370890 (+)	474	WP_017369377.1	transcription elongation factor GreA	-
ACL43R_RS01865 (ACL43R_01865)	-	371010..371462 (+)	453	WP_165711882.1	CtsR family transcriptional regulator	-
ACL43R_RS01870 (ACL43R_01870)	clpC	371452..373902 (+)	2451	WP_185767512.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
ACL43R_RS01875 (ACL43R_01875)	hpf	374025..374582 (+)	558	WP_003134010.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
ACL43R_RS01880 (ACL43R_01880)	pflB	374830..377163 (+)	2334	WP_019292664.1	formate C-acetyltransferase	-
ACL43R_RS01885 (ACL43R_01885)	coaE	377625..378230 (+)	606	WP_096368656.1	dephospho-CoA kinase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 91106.33 Da
• Isoelectric Point: 6.0545

>NTDB_id=1097141 ACL43R_RS01870 WP_185767512.1 371452..373902(+) (clpC) [Lactococcus formosensis strain JAL11]
MKFNEKDYTPQVIRVLEKSVDYAHKFNYAWVESSHLLAALAEVPASLAFTLLNSEKIDLEEMLIDIEDFSSQVKTKKSEI
KLSPRVEAIIEQARALAQNNDKNRIGTEHLLYMLLANDAGFAGQLLREQNINIVNLRKKLEQKAYLRVPERRKAVTPASK
RNLSGKVSETTTTPTLDTVSTDLTKAAREGKLDPMIGREREVERLIHILSRRTKNNPVLVGEPGVGKSAIIEGFATRVAA
GDVPVGLRGSRIMALNMAMVVAGTKFRGEFEDRLTAIVDEVTHDKDVIVFIDELHTIIGAGGGMDSVNDASNILKPALAR
GEFQLIGATTYQEYQKYIEKDEALERRFARVNVEEPSEDETVAILQGLKEKFEAYHAVKFEEGTLERAVSLSNRYMPSRR
LPDKAIDLLDEAAAKVKITSKTNYTKLDELKAELKAEELRLQKAVVALDIVEAQGIEKDIEKLTHKIDNFTVSENDNPLV
EESDVYAVVSNLTGIPLQQMTKTESERLINLEKELHKRVVGQEEAISAVSRAIRRARSGIADTRRPLGSFMFLGPTGVGK
TELAKALAESVFGSEENMIRVDMSEFMEKFSTSRLIGAPPGYVGYDEGGQLTEQVRNKPYSVILLDEVEKAHPDIFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATAIRDDKTVGFGAKSISTDYAAMKARIMEELKKQYRPEFLNRIDETIVF
HSLTEKEIEQVVKIMSKSLVSRLKDQNIKVKFTPAALKVIADKGFDPEYGARPLRKALQREVEDTLSEQLLAGEIHPGDT
ISIGSSNKKIRISVID

Nucleotide

• Length: 2451 bp

>NTDB_id=1097141 ACL43R_RS01870 WP_185767512.1 371452..373902(+) (clpC) [Lactococcus formosensis strain JAL11]
ATGAAATTTAATGAAAAGGACTATACACCACAAGTCATAAGAGTGCTTGAGAAGTCTGTTGACTATGCGCATAAGTTTAA
CTACGCTTGGGTTGAAAGCTCGCACCTATTGGCTGCATTGGCTGAGGTTCCGGCTTCATTGGCATTTACGCTACTTAATT
CAGAAAAAATTGATTTGGAAGAAATGTTAATCGACATTGAAGATTTTTCAAGTCAAGTGAAGACGAAGAAATCAGAAATA
AAGCTTAGCCCAAGAGTTGAGGCAATTATTGAACAAGCACGTGCATTGGCTCAAAACAACGATAAAAACCGTATCGGGAC
AGAGCATCTCTTGTATATGCTTTTAGCAAATGATGCTGGCTTTGCAGGACAACTTTTACGTGAGCAAAACATCAATATCG
TTAACCTCCGTAAAAAGCTAGAGCAAAAAGCATATCTACGTGTACCAGAACGCCGTAAAGCGGTGACACCAGCTTCGAAA
AGAAACTTGTCAGGTAAAGTTTCCGAAACCACGACAACGCCTACTTTAGACACGGTATCGACAGATTTGACAAAAGCAGC
CCGTGAAGGCAAGCTTGATCCAATGATTGGAAGAGAGCGAGAAGTCGAACGCCTCATCCACATTTTGAGTCGTCGGACAA
AGAATAATCCTGTTCTTGTTGGTGAACCTGGTGTTGGTAAGTCAGCGATTATTGAAGGCTTTGCGACGCGTGTGGCTGCA
GGGGATGTTCCTGTAGGTTTACGTGGCAGTCGTATCATGGCTTTGAATATGGCGATGGTTGTTGCGGGGACAAAATTCCG
TGGTGAATTTGAAGATCGTTTGACAGCTATCGTTGATGAAGTGACACATGATAAAGATGTGATCGTCTTTATCGATGAAC
TTCATACCATTATCGGTGCTGGTGGAGGTATGGATTCTGTTAATGATGCTTCCAATATCTTAAAACCGGCATTAGCACGT
GGTGAGTTTCAACTTATTGGGGCAACAACTTATCAAGAATATCAAAAATATATTGAAAAAGATGAGGCCCTAGAACGTCG
TTTTGCCCGTGTTAATGTTGAAGAACCATCAGAAGATGAAACAGTTGCAATCTTACAAGGGTTAAAAGAAAAATTTGAAG
CTTACCATGCGGTCAAATTTGAAGAGGGAACTTTGGAACGTGCCGTCAGTCTGAGCAATCGTTATATGCCAAGTCGTCGT
CTGCCAGATAAAGCAATTGATCTCCTTGATGAAGCCGCAGCCAAAGTTAAAATTACGAGTAAAACAAATTACACCAAGCT
TGACGAATTAAAAGCGGAGTTAAAAGCAGAAGAGCTGAGATTACAAAAAGCAGTTGTAGCACTTGATATTGTTGAAGCAC
AGGGGATTGAAAAAGATATTGAAAAGTTAACGCATAAAATTGATAACTTTACAGTATCGGAAAATGATAATCCTTTGGTT
GAGGAAAGCGATGTTTATGCTGTCGTTTCCAACCTTACAGGGATTCCTCTCCAACAGATGACGAAAACAGAAAGTGAACG
TCTGATTAATCTAGAAAAAGAGTTACATAAGCGTGTAGTTGGACAGGAAGAAGCGATATCGGCTGTTTCTCGTGCCATAA
GACGTGCACGTTCAGGTATCGCCGATACGAGACGCCCTTTGGGTTCATTTATGTTCCTTGGTCCGACAGGGGTTGGGAAG
ACAGAGCTTGCTAAGGCTTTAGCGGAAAGTGTTTTTGGCAGTGAAGAAAACATGATTCGCGTAGACATGAGTGAATTTAT
GGAAAAATTCTCTACATCACGCCTGATTGGAGCGCCTCCAGGCTACGTAGGTTATGATGAAGGGGGACAACTAACAGAGC
AAGTCCGCAATAAGCCTTATTCTGTTATCCTTCTTGATGAAGTCGAAAAGGCCCATCCTGATATTTTCAATATCATGTTA
CAAATTCTAGATGATGGTTTCGTTACAGACACGAAGGGTCGTAAAGTTGATTTCAGAAATACGATTATCATTATGACATC
TAACCTTGGTGCAACAGCTATTCGTGATGATAAAACAGTTGGTTTTGGTGCCAAATCAATCTCAACAGACTATGCAGCTA
TGAAAGCGAGAATCATGGAAGAACTGAAGAAACAGTACCGTCCAGAATTTCTCAATCGTATCGATGAAACTATCGTTTTC
CATTCACTGACAGAAAAAGAGATTGAACAAGTCGTGAAAATTATGAGTAAATCTCTCGTATCACGCTTGAAAGATCAAAA
TATCAAAGTGAAATTTACACCTGCTGCTTTGAAAGTTATTGCTGATAAAGGATTTGATCCTGAATACGGCGCCCGCCCAT
TGCGTAAAGCTCTGCAACGTGAGGTTGAAGACACGCTCAGTGAGCAATTGCTTGCCGGCGAAATTCATCCGGGGGATACG
ATTTCTATTGGTTCTTCTAATAAAAAGATTAGAATAAGTGTTATTGATTGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-349)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (22-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (93-142)

• AAA lid domain (AAA_lid_9) (357-445)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	71.166	99.877	0.711
clpC	Streptococcus thermophilus LMG 18311	49.11	100	0.507
clpC	Streptococcus thermophilus LMD-9	49.11	100	0.507
clpC	Streptococcus pneumoniae TIGR4	49.395	100	0.5
clpC	Streptococcus pneumoniae Rx1	49.274	100	0.499
clpC	Streptococcus pneumoniae D39	49.274	100	0.499
clpC	Streptococcus mutans UA159	47.368	100	0.485
clpC	Bacillus subtilis subsp. subtilis str. 168	48.439	98.162	0.475
clpE	Streptococcus mutans UA159	46.719	78.431	0.366