Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   HV95_RS07500 Genome accession   NZ_CP008864
Coordinates   1591592..1594441 (-) Length   949 a.a.
NCBI ID   WP_023083185.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain W60856     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 1586592..1599441
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HV95_RS07480 (HV95_01060) yfdX1 1586821..1587729 (-) 909 WP_019485625.1 heat resistance protein YfdX1 -
  HV95_RS07485 (HV95_01065) hsp20-GI 1587751..1588209 (-) 459 WP_019485624.1 small heat shock protein sHSP20-GI -
  HV95_RS07490 (HV95_01070) ftsH 1588288..1590117 (-) 1830 WP_023083187.1 ATP-dependent zinc metalloprotease FtsH -
  HV95_RS07495 (HV95_01075) cls 1590145..1591575 (-) 1431 WP_023083186.1 cardiolipin synthase -
  HV95_RS07500 (HV95_01080) clpC 1591592..1594441 (-) 2850 WP_023083185.1 heat shock survival AAA family ATPase ClpK Regulator
  HV95_RS07505 (HV95_01085) - 1594535..1595104 (-) 570 WP_023083184.1 Hsp20/alpha crystallin family protein -
  HV95_RS07510 (HV95_32490) - 1595149..1595421 (-) 273 Protein_1448 helix-turn-helix domain-containing protein -
  HV95_RS33555 (HV95_01090) - 1595766..1595999 (+) 234 Protein_1449 IS110 family transposase -
  HV95_RS33315 - 1596121..1596550 (-) 430 Protein_1450 IS66 family transposase -
  HV95_RS07530 (HV95_01105) - 1596690..1597598 (+) 909 WP_012761385.1 LysR family transcriptional regulator -
  HV95_RS07535 (HV95_01110) - 1598138..1598896 (+) 759 WP_003454930.1 hypothetical protein -
  HV95_RS07540 (HV95_01115) - 1599038..1599256 (+) 219 WP_016852009.1 AlpA family transcriptional regulator -

Sequence

Protein


Download         Length: 949 a.a.        Molecular weight: 104324.16 Da        Isoelectric Point: 5.8094

>NTDB_id=109713 HV95_RS07500 WP_023083185.1 1591592..1594441(-) (clpC) [Pseudomonas aeruginosa strain W60856]
MARKQCQVCGQSATVRVEANLNGRHSTMLLCDDHYRQLARQQKRTVSPLEALFGSRSGLFEDFLGSDFFRIGDDAPSVAA
DADEVVDASFGESAPATAGTARRRGSGLASRISEQSEALLQEAARHAAEFGRAEVDTEHLLLALSDSDVVKTILGQFKIK
VDDLKRQIESEAKRGDKPFEGEIGVSPRVKDALSRAFVASNELGHSYVGPEHFLIGLAEEGEGLAANLLRRYGLTPQALR
QQVSKVVGKGAEDGRAETPTNTPELDKYSRDLTKMAREGKLDPVIGRAQEIETTIEVLARRKKNNPVLIGEPGVGKTAIV
EGLAQRMVAGEVPETLRDKRLVELNINAMVAGAKYRGEFEERVQKVLKEVTEHQGELILFIDEVHTIVGAGQGGGEGGLD
VANVFKPMMARGELNLIGATTLNEYQKYIEKDAALERRFQPVMVPEPTIAQTMMILRGLRDTFEAHHKVSITEDAIIAAA
ELSDRYITARFLPDKAIDLLDQAAARVKLSATARPVAVQELESELHQLRREQDYVASRKQYDKAAELGKRIEAKETELKK
LVEEWERERASGSAEVKAEHVAQIVSRLTGIPVNELTVEEREKLLHLEQRLHERLVGQDEAVRAVADAVRLSRAGLREGG
KPVATFLFLGPTGVGKTELAKALAESIYGDEGALLRIDMSEYGERHTVARLVGAPPGYVGYDEGGQLTEKVRRKPYSVLL
LDEIEKAHPDVYNILLQVFDDGRLTDGKGRVVDFTNTIIIATSNLGSDIIQRRLKARGAAGEEYEKTKSEVMDVLRGHFR
PEFLNRIDEIIVFHALGKEEIRHIVGLQLDRVARNAASQGVTLTFDQTLIDHFAEEGYKPEFGARELKRLIRSELETALA
REMLGGGIGKADHASARWDDKAERVVFERQEPAAQPAEPEKPDAANVAEAPPNGESKPARKKKSAGGGS

Nucleotide


Download         Length: 2850 bp        

>NTDB_id=109713 HV95_RS07500 WP_023083185.1 1591592..1594441(-) (clpC) [Pseudomonas aeruginosa strain W60856]
ATGGCCAGAAAACAATGCCAAGTCTGCGGCCAGTCCGCCACGGTGCGGGTGGAAGCCAATCTCAATGGTCGCCACAGCAC
CATGCTGTTGTGTGACGATCACTATCGCCAACTGGCGCGCCAGCAAAAGCGCACCGTCTCGCCGCTGGAGGCTCTGTTTG
GCTCGCGCAGCGGTTTGTTCGAAGACTTCCTCGGCAGCGACTTCTTCCGCATCGGTGACGATGCACCGTCCGTGGCGGCT
GATGCCGACGAAGTGGTCGATGCGTCTTTCGGCGAATCCGCTCCCGCAACGGCGGGCACGGCGCGCCGCCGCGGCAGTGG
GCTGGCCAGCCGTATCAGCGAACAGTCCGAGGCCCTATTGCAGGAGGCCGCCCGACACGCTGCAGAGTTCGGGCGCGCCG
AAGTCGATACCGAACACCTGCTGCTGGCGCTATCCGACAGCGACGTGGTCAAGACCATCCTGGGGCAGTTCAAGATCAAG
GTCGATGACCTCAAGCGCCAGATCGAATCCGAAGCCAAGCGCGGCGATAAGCCGTTCGAGGGCGAGATCGGCGTGTCGCC
CCGGGTCAAGGACGCGCTCAGCCGTGCTTTCGTGGCCTCCAACGAACTCGGCCACTCTTATGTCGGGCCGGAGCATTTCC
TGATCGGGCTCGCCGAGGAAGGCGAAGGTTTGGCGGCCAACCTGCTGCGCCGTTACGGCCTCACGCCGCAAGCGCTGCGC
CAGCAGGTAAGCAAGGTGGTCGGCAAAGGGGCCGAGGATGGCCGCGCCGAGACGCCGACCAACACGCCGGAACTCGACAA
GTATTCGCGCGACCTCACCAAGATGGCGCGCGAGGGCAAGCTCGATCCGGTCATCGGCCGCGCGCAGGAGATCGAGACGA
CCATCGAAGTGCTGGCCCGGCGCAAGAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCGGCAAGACCGCCATCGTC
GAAGGGCTGGCGCAGCGCATGGTCGCCGGCGAAGTGCCCGAGACGCTGCGCGACAAGCGCCTGGTGGAACTCAACATCAA
TGCCATGGTGGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAGCGCGTGCAGAAGGTGCTCAAGGAAGTGACCGAGCACC
AGGGCGAGCTGATTCTCTTCATCGACGAAGTGCACACCATCGTCGGTGCAGGCCAGGGTGGCGGCGAAGGCGGGCTGGAC
GTGGCCAACGTGTTCAAGCCGATGATGGCGCGCGGCGAACTGAACCTGATCGGCGCCACCACGCTCAACGAGTATCAGAA
GTACATCGAGAAGGACGCCGCGCTGGAGCGTCGCTTCCAGCCGGTGATGGTGCCCGAGCCGACGATAGCGCAGACCATGA
TGATCCTGCGCGGCCTGCGCGACACCTTCGAGGCGCACCACAAGGTCAGCATCACCGAGGATGCGATCATCGCCGCCGCC
GAGTTGTCGGACCGCTACATCACCGCGCGCTTTTTGCCTGACAAGGCCATCGACCTGCTCGACCAGGCGGCCGCACGCGT
GAAGCTGTCGGCCACGGCCCGCCCGGTGGCGGTGCAAGAGCTGGAGTCCGAACTGCACCAGCTGCGGCGTGAGCAAGACT
ATGTGGCTTCGCGCAAGCAGTACGACAAGGCCGCCGAGCTGGGCAAGCGCATCGAGGCCAAGGAGACTGAACTCAAGAAG
CTCGTCGAGGAATGGGAACGCGAGCGCGCCTCGGGCAGCGCCGAAGTCAAGGCCGAGCATGTCGCGCAGATCGTCTCGCG
CCTGACCGGCATTCCGGTCAACGAGCTGACGGTGGAAGAACGCGAGAAGCTGCTGCATCTGGAGCAGCGGCTGCACGAGC
GCCTGGTGGGCCAGGACGAAGCAGTACGTGCCGTGGCCGATGCCGTGCGGCTGTCGCGCGCGGGCCTGCGCGAAGGCGGC
AAGCCAGTGGCCACCTTCCTGTTCCTCGGGCCGACGGGTGTGGGCAAGACCGAACTCGCCAAGGCACTGGCCGAGTCCAT
CTATGGCGATGAGGGCGCGCTGCTGCGCATCGACATGTCCGAGTACGGTGAACGCCATACCGTGGCACGCCTGGTGGGCG
CGCCTCCGGGTTATGTGGGCTATGACGAGGGCGGCCAGCTCACCGAGAAGGTGCGTCGCAAACCCTACAGCGTGTTGTTG
CTCGATGAGATCGAAAAAGCGCACCCCGACGTCTACAACATCCTGCTGCAGGTATTCGACGACGGGCGGCTCACCGACGG
CAAGGGCCGGGTGGTGGATTTCACCAATACCATCATCATCGCCACCTCGAACTTGGGCTCGGACATCATCCAGCGTCGGC
TGAAGGCCCGTGGCGCCGCCGGCGAGGAATACGAGAAGACCAAGTCCGAGGTGATGGACGTGCTGCGCGGACACTTCCGC
CCCGAGTTCCTCAACCGCATCGACGAGATCATCGTCTTCCATGCGCTGGGCAAGGAGGAGATCCGCCATATCGTCGGCCT
GCAGCTCGATCGTGTGGCCCGCAACGCCGCCAGCCAGGGCGTGACGTTGACCTTCGACCAGACCTTGATCGACCACTTCG
CGGAGGAAGGCTACAAACCCGAGTTCGGCGCGCGCGAGCTCAAGCGGCTGATCCGCAGCGAGCTGGAAACCGCGCTGGCA
CGCGAGATGCTCGGTGGTGGCATCGGCAAGGCCGATCACGCCAGCGCCCGCTGGGATGACAAGGCCGAACGGGTGGTCTT
CGAGCGCCAGGAGCCAGCCGCGCAGCCGGCCGAGCCTGAAAAGCCCGATGCAGCGAACGTGGCCGAGGCACCGCCGAACG
GCGAGAGCAAGCCTGCGCGCAAGAAGAAGTCAGCGGGCGGCGGATCTTGA

Domains

Predicted by InterProScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(123-171)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(199-248)

ATPase family associated with various cellular activities (AAA) (AAA)

(307-440)

AAA domain (Cdc48 subfamily) (AAA_2)

(641-810)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(816-894)

AAA lid domain (AAA_lid_9)

(449-547)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Bacillus subtilis subsp. subtilis str. 168

50.692

83.772

0.425
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.59

86.301

0.376
  clpC Streptococcus thermophilus LMD-9

41.869

86.828

0.364
  clpC Streptococcus mutans UA159

42.086

85.88

0.361
  clpC Streptococcus thermophilus LMG 18311

41.778

86.512

0.361

Multiple sequence alignment