Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACK2OW_RS13305 Genome accession   NZ_CP180575
Coordinates   2482002..2482658 (+) Length   218 a.a.
NCBI ID   WP_003232942.1    Uniprot ID   A0AAQ3ENL6
Organism   Bacillus subtilis strain K3C     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2477002..2487658
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK2OW_RS13275 (ACK2OW_13275) oppF 2477464..2478381 (+) 918 WP_003239287.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ACK2OW_RS13280 (ACK2OW_13280) yjbB 2478488..2479705 (+) 1218 WP_072175656.1 MFS transporter -
  ACK2OW_RS13285 (ACK2OW_13285) yjbC 2479869..2480447 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  ACK2OW_RS13290 (ACK2OW_13290) spx 2480628..2481023 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  ACK2OW_RS13295 (ACK2OW_13295) yjbE 2481069..2481725 (-) 657 WP_003232944.1 TerC family protein -
  ACK2OW_RS13300 (ACK2OW_13300) - 2481895..2482035 (+) 141 WP_163138320.1 hypothetical protein -
  ACK2OW_RS13305 (ACK2OW_13305) mecA 2482002..2482658 (+) 657 WP_003232942.1 adaptor protein MecA Regulator
  ACK2OW_RS13310 (ACK2OW_13310) - 2482653..2482775 (-) 123 WP_161621487.1 hypothetical protein -
  ACK2OW_RS13315 (ACK2OW_13315) coiA 2482819..2483970 (+) 1152 WP_411225631.1 competence protein CoiA Machinery gene
  ACK2OW_RS13320 (ACK2OW_13320) pepF 2484200..2486029 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  ACK2OW_RS13325 (ACK2OW_13325) - 2486067..2486234 (-) 168 WP_003244944.1 hypothetical protein -
  ACK2OW_RS13330 (ACK2OW_13330) spxH 2486549..2487448 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25762.62 Da        Isoelectric Point: 4.0841

>NTDB_id=1096794 ACK2OW_RS13305 WP_003232942.1 2482002..2482658(+) (mecA) [Bacillus subtilis strain K3C]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1096794 ACK2OW_RS13305 WP_003232942.1 2482002..2482658(+) (mecA) [Bacillus subtilis strain K3C]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991

Multiple sequence alignment