Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACMX8W_RS06280 Genome accession   NZ_CP180439
Coordinates   1215464..1216120 (+) Length   218 a.a.
NCBI ID   WP_015383354.1    Uniprot ID   -
Organism   Bacillus subtilis strain Z-294     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1210464..1221120
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACMX8W_RS06250 (ACMX8W_06250) oppF 1210929..1211846 (+) 918 WP_047182432.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ACMX8W_RS06255 (ACMX8W_06255) yjbB 1211950..1213167 (+) 1218 WP_080344185.1 MFS transporter -
  ACMX8W_RS06260 (ACMX8W_06260) yjbC 1213331..1213909 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  ACMX8W_RS06265 (ACMX8W_06265) spx 1214090..1214485 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  ACMX8W_RS06270 (ACMX8W_06270) yjbE 1214531..1215187 (-) 657 WP_003232944.1 TerC family protein -
  ACMX8W_RS06275 (ACMX8W_06275) - 1215357..1215497 (+) 141 WP_119122854.1 hypothetical protein -
  ACMX8W_RS06280 (ACMX8W_06280) mecA 1215464..1216120 (+) 657 WP_015383354.1 adaptor protein MecA Regulator
  ACMX8W_RS06285 (ACMX8W_06285) - 1216115..1216236 (-) 122 Protein_1173 hypothetical protein -
  ACMX8W_RS06290 (ACMX8W_06290) coiA 1216280..1217431 (+) 1152 WP_047182434.1 competence protein CoiA Machinery gene
  ACMX8W_RS06295 (ACMX8W_06295) pepF 1217661..1219490 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  ACMX8W_RS06300 (ACMX8W_06300) - 1219528..1219695 (-) 168 WP_003244944.1 hypothetical protein -
  ACMX8W_RS06305 (ACMX8W_06305) spxH 1220010..1220909 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25749.62 Da        Isoelectric Point: 4.0841

>NTDB_id=1095862 ACMX8W_RS06280 WP_015383354.1 1215464..1216120(+) (mecA) [Bacillus subtilis strain Z-294]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1095862 ACMX8W_RS06280 WP_015383354.1 1215464..1216120(+) (mecA) [Bacillus subtilis strain Z-294]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995

Multiple sequence alignment