Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACMX2G_RS14585 Genome accession   NZ_CP180375
Coordinates   2870407..2871063 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain NJN-6     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2865407..2876063
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACMX2G_RS14555 (ACMX2G_14555) - 2866908..2867843 (+) 936 WP_003155043.1 ABC transporter permease -
  ACMX2G_RS14560 (ACMX2G_14560) - 2867847..2868299 (+) 453 Protein_2796 ABC transporter permease -
  ACMX2G_RS14565 (ACMX2G_14565) - 2868310..2868843 (+) 534 WP_184123308.1 GNAT family N-acetyltransferase -
  ACMX2G_RS14570 (ACMX2G_14570) spx 2869022..2869417 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  ACMX2G_RS14575 (ACMX2G_14575) - 2869475..2870131 (-) 657 WP_003155033.1 TerC family protein -
  ACMX2G_RS14580 (ACMX2G_14580) - 2870314..2870424 (+) 111 Protein_2800 adaptor protein MecA -
  ACMX2G_RS14585 (ACMX2G_14585) mecA 2870407..2871063 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  ACMX2G_RS14590 (ACMX2G_14590) - 2871214..2872374 (+) 1161 WP_024085124.1 competence protein CoiA family protein -
  ACMX2G_RS14595 (ACMX2G_14595) pepF 2872602..2874431 (+) 1830 WP_024085125.1 oligoendopeptidase F Regulator
  ACMX2G_RS14600 (ACMX2G_14600) - 2874469..2874636 (-) 168 WP_003155026.1 hypothetical protein -
  ACMX2G_RS14605 (ACMX2G_14605) spxH 2874922..2875824 (-) 903 WP_024085126.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=1095503 ACMX2G_RS14585 WP_003155032.1 2870407..2871063(+) (mecA) [Bacillus velezensis strain NJN-6]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1095503 ACMX2G_RS14585 WP_003155032.1 2870407..2871063(+) (mecA) [Bacillus velezensis strain NJN-6]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTAGTGATCGCTGATCATGCGTTATATACAATAAAAA
AGCACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment