Detailed information NTG1095159

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACMVYM_RS05450
• Genome accession: NZ_CP180297
• Coordinates: 1138968..1140014 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain YSMAS1_1_C10
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1133968..1145014

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACMVYM_RS05420 (ACMVYM_05420)	-	1134352..1135593 (-)	1242	WP_337229091.1	aminopeptidase	-
ACMVYM_RS05425 (ACMVYM_05425)	-	1135595..1135810 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
ACMVYM_RS05430 (ACMVYM_05430)	-	1135951..1136415 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
ACMVYM_RS05435 (ACMVYM_05435)	-	1136423..1136707 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
ACMVYM_RS05440 (ACMVYM_05440)	-	1137114..1138292 (+)	1179	WP_021298785.1	YihY/virulence factor BrkB family protein	-
ACMVYM_RS05445 (ACMVYM_05445)	vraR	1138349..1138978 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
ACMVYM_RS05450 (ACMVYM_05450)	vraS	1138968..1140014 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
ACMVYM_RS05455 (ACMVYM_05455)	liaF	1140011..1140712 (-)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
ACMVYM_RS05460 (ACMVYM_05460)	-	1140726..1141112 (-)	387	WP_001830382.1	hypothetical protein	-
ACMVYM_RS05465 (ACMVYM_05465)	map	1141270..1142025 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
ACMVYM_RS05470 (ACMVYM_05470)	-	1142199..1143185 (+)	987	WP_002457091.1	FUSC family protein	-
ACMVYM_RS05475 (ACMVYM_05475)	isaB	1143336..1143872 (-)	537	WP_001830372.1	immunodominant staphylococcal antigen IsaB family protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=1095159 ACMVYM_RS05450 WP_001830374.1 1138968..1140014(-) (vraS) [Staphylococcus epidermidis strain YSMAS1_1_C10]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=1095159 ACMVYM_RS05450 WP_001830374.1 1138968..1140014(-) (vraS) [Staphylococcus epidermidis strain YSMAS1_1_C10]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92