Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ACMVYP_RS11235 Genome accession   NZ_CP180295
Coordinates   2229462..2230178 (+) Length   238 a.a.
NCBI ID   WP_002455088.1    Uniprot ID   -
Organism   Staphylococcus hominis strain YSMAS1_1_A7     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2224462..2235178
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACMVYP_RS11210 (ACMVYP_11210) - 2225185..2225808 (+) 624 WP_017175275.1 nitroreductase family protein -
  ACMVYP_RS11215 (ACMVYP_11215) - 2225939..2226724 (+) 786 WP_017175276.1 carbon-nitrogen family hydrolase -
  ACMVYP_RS11220 (ACMVYP_11220) - 2227426..2227992 (+) 567 WP_017175277.1 accessory gene regulator AgrB -
  ACMVYP_RS11225 (ACMVYP_11225) agrD 2227995..2228135 (+) 141 WP_017175278.1 cyclic lactone autoinducer peptide AgrD -
  ACMVYP_RS11230 (ACMVYP_11230) agrC 2228160..2229449 (+) 1290 WP_017175279.1 quorum-sensing sensor histidine kinase AgrC -
  ACMVYP_RS11235 (ACMVYP_11235) agrA 2229462..2230178 (+) 717 WP_002455088.1 quorum-sensing response regulator AgrA Regulator
  ACMVYP_RS11240 (ACMVYP_11240) - 2230229..2231180 (-) 952 Protein_2163 carbohydrate kinase family protein -
  ACMVYP_RS11245 (ACMVYP_11245) - 2231181..2232668 (-) 1488 WP_017175281.1 sucrose-6-phosphate hydrolase -
  ACMVYP_RS11250 (ACMVYP_11250) - 2232923..2234167 (-) 1245 WP_017175282.1 ammonium transporter -
  ACMVYP_RS11255 (ACMVYP_11255) - 2234277..2234435 (-) 159 Protein_2166 sulfurtransferase TusA family protein -
  ACMVYP_RS11260 (ACMVYP_11260) - 2234502..2235140 (-) 639 WP_017175284.1 redox-sensing transcriptional repressor Rex -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27858.75 Da        Isoelectric Point: 5.2104

>NTDB_id=1095102 ACMVYP_RS11235 WP_002455088.1 2229462..2230178(+) (agrA) [Staphylococcus hominis strain YSMAS1_1_A7]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEIIEQSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPNQLKTRIIDCIETAHTRLKLLSKESNVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDDRFFRCHNSFVVNRHNIDSVDSKERIVTFRNGEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1095102 ACMVYP_RS11235 WP_002455088.1 2229462..2230178(+) (agrA) [Staphylococcus hominis strain YSMAS1_1_A7]
ATGAAAATATTCATTTGTGAAGACGATGTGAAACAACGTGAAAATATGGTTTCAATTATTAATAACTATATAATGATTGA
AGAAAAACCGATGGAAATAGCGTTAGCGACAGATGATCCTTATGAAATTATTGAACAGTCAAAAGAAATGAATGATGTTG
GATGTTATTTTTTAGATATACAATTAGAAGCTGATATTAACGGTATTAAACTTGGAAGTGAAATTCGAAAGTATGATCCT
ATTGGGAATATCATCTTTGTTACAAGTCATAGTGAACTCACTTACCTAACATTTGTCTATAAGGTATCGGCAATGGATTT
TATTTTTAAAGATGATCCTAATCAACTTAAAACGCGAATAATAGATTGTATTGAAACTGCTCATACACGTTTAAAATTAC
TTTCAAAAGAAAGTAATGTTGAGACAATTGAATTAAAGCGTGGTAGCAATTCAATATATGTACAATATGATGATGTCATG
TTCTTTGAATCGTCTACAAAATCCCATCGTTTAATTGCGCATCTTGATAACCGTCAGATTGAATTCTACGGAAATCTTAA
AGAATTAGCACAACTCGATGATCGTTTTTTCAGATGTCACAATAGTTTTGTTGTAAATCGCCATAATATCGATTCAGTCG
ATTCTAAAGAACGAATTGTAACTTTCAGAAATGGTGAGCATTGCTATGCCTCTGTACGTAATGTTAAAAAGATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874

Multiple sequence alignment