Detailed information
Bioinformatically predicted
Overview
| Name | nucA/comI | Type | Machinery gene |
| Locus tag | ACLCDX_RS08845 | Genome accession | NZ_CP180263 |
| Coordinates | 1768584..1768964 (+) | Length | 126 a.a. |
| NCBI ID | WP_051149980.1 | Uniprot ID | - |
| Organism | Bacillus safensis strain BS22LVI | ||
| Function | cleavage of dsDNA into ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1735383..1773378 | 1768584..1768964 | within | 0 |
Gene organization within MGE regions
Location: 1735383..1773378
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ACLCDX_RS08675 (ACLCDX_08675) | - | 1735383..1736222 (+) | 840 | WP_024424079.1 | hypothetical protein | - |
| ACLCDX_RS08680 (ACLCDX_08680) | - | 1736267..1736648 (+) | 382 | Protein_1661 | ArpU family phage packaging/lysis transcriptional regulator | - |
| ACLCDX_RS08685 (ACLCDX_08685) | - | 1736778..1738378 (+) | 1601 | Protein_1662 | ribonuclease YeeF family protein | - |
| ACLCDX_RS08690 (ACLCDX_08690) | - | 1738383..1738766 (+) | 384 | WP_024425095.1 | immunity 22 family protein | - |
| ACLCDX_RS08695 (ACLCDX_08695) | - | 1738840..1739244 (+) | 405 | WP_024425096.1 | hypothetical protein | - |
| ACLCDX_RS08700 (ACLCDX_08700) | - | 1739712..1739891 (+) | 180 | WP_024425097.1 | hypothetical protein | - |
| ACLCDX_RS08705 (ACLCDX_08705) | - | 1739983..1740327 (+) | 345 | WP_024425098.1 | hypothetical protein | - |
| ACLCDX_RS08710 (ACLCDX_08710) | - | 1740644..1741012 (+) | 369 | WP_024425099.1 | nuclear transport factor 2 family protein | - |
| ACLCDX_RS08715 (ACLCDX_08715) | - | 1741661..1741837 (+) | 177 | WP_258011175.1 | ParB N-terminal domain-containing protein | - |
| ACLCDX_RS08720 (ACLCDX_08720) | - | 1741853..1742362 (+) | 510 | WP_024425101.1 | phage minor head protein | - |
| ACLCDX_RS08725 (ACLCDX_08725) | - | 1742405..1743055 (+) | 651 | WP_024425102.1 | hypothetical protein | - |
| ACLCDX_RS08730 (ACLCDX_08730) | - | 1743093..1744111 (+) | 1019 | Protein_1671 | XkdF-like putative serine protease domain-containing protein | - |
| ACLCDX_RS08735 (ACLCDX_08735) | - | 1744421..1745038 (+) | 618 | WP_134817554.1 | hypothetical protein | - |
| ACLCDX_RS08740 (ACLCDX_08740) | - | 1745270..1745689 (+) | 420 | WP_024425104.1 | hypothetical protein | - |
| ACLCDX_RS08745 (ACLCDX_08745) | - | 1746066..1747991 (+) | 1926 | WP_024425105.1 | T7SS effector LXG polymorphic toxin | - |
| ACLCDX_RS08750 (ACLCDX_08750) | - | 1747995..1748471 (+) | 477 | WP_024425106.1 | immunity protein YezG family protein | - |
| ACLCDX_RS08755 (ACLCDX_08755) | - | 1748536..1748997 (-) | 462 | WP_024425107.1 | macro domain-containing protein | - |
| ACLCDX_RS08760 (ACLCDX_08760) | - | 1749226..1749807 (+) | 582 | WP_024425108.1 | undecaprenyl-diphosphatase | - |
| ACLCDX_RS08765 (ACLCDX_08765) | - | 1749858..1750229 (-) | 372 | WP_024425109.1 | iron chaperone | - |
| ACLCDX_RS08770 (ACLCDX_08770) | - | 1750771..1751883 (+) | 1113 | WP_024425110.1 | tetratricopeptide repeat protein | - |
| ACLCDX_RS08775 (ACLCDX_08775) | - | 1752613..1753308 (-) | 696 | WP_087978168.1 | YoaK family protein | - |
| ACLCDX_RS08780 (ACLCDX_08780) | - | 1753376..1755207 (-) | 1832 | Protein_1681 | DNA ligase D | - |
| ACLCDX_RS08785 (ACLCDX_08785) | - | 1755323..1756171 (+) | 849 | WP_024425113.1 | Ku protein | - |
| ACLCDX_RS08790 (ACLCDX_08790) | - | 1756388..1756831 (-) | 444 | WP_024425114.1 | DUF2188 domain-containing protein | - |
| ACLCDX_RS08795 (ACLCDX_08795) | - | 1756997..1757470 (+) | 474 | WP_051170147.1 | VOC family protein | - |
| ACLCDX_RS08800 (ACLCDX_08800) | - | 1757519..1757932 (+) | 414 | WP_024425116.1 | Rrf2 family transcriptional regulator | - |
| ACLCDX_RS08805 (ACLCDX_08805) | - | 1758033..1758884 (+) | 852 | WP_024425117.1 | SDR family oxidoreductase | - |
| ACLCDX_RS08810 (ACLCDX_08810) | - | 1759039..1759947 (+) | 909 | WP_024425118.1 | DMT family transporter | - |
| ACLCDX_RS08815 (ACLCDX_08815) | - | 1759960..1760151 (-) | 192 | WP_024425119.1 | hypothetical protein | - |
| ACLCDX_RS08820 (ACLCDX_08820) | - | 1760262..1762478 (+) | 2217 | WP_024425120.1 | RNA ligase | - |
| ACLCDX_RS08825 (ACLCDX_08825) | - | 1762543..1763253 (+) | 711 | WP_024425121.1 | DUF421 domain-containing protein | - |
| ACLCDX_RS08830 (ACLCDX_08830) | - | 1763480..1764058 (+) | 579 | WP_024425122.1 | TetR/AcrR family transcriptional regulator | - |
| ACLCDX_RS08835 (ACLCDX_08835) | - | 1764080..1767223 (+) | 3144 | WP_149126620.1 | bifunctional cytochrome P450/NADPH--P450 reductase | - |
| ACLCDX_RS08840 (ACLCDX_08840) | - | 1767417..1768325 (+) | 909 | WP_024425124.1 | trypsin-like serine peptidase | - |
| ACLCDX_RS08845 (ACLCDX_08845) | nucA/comI | 1768584..1768964 (+) | 381 | WP_051149980.1 | NucA/NucB deoxyribonuclease domain-containing protein | Machinery gene |
| ACLCDX_RS08850 (ACLCDX_08850) | - | 1769110..1769958 (+) | 849 | WP_025093249.1 | STAS domain-containing protein | - |
| ACLCDX_RS08855 (ACLCDX_08855) | - | 1769991..1770533 (-) | 543 | WP_025093248.1 | IseA DL-endopeptidase inhibitor family protein | - |
| ACLCDX_RS08860 (ACLCDX_08860) | - | 1770829..1771278 (+) | 450 | WP_415316265.1 | hypothetical protein | - |
| ACLCDX_RS08865 (ACLCDX_08865) | lexA | 1771323..1771943 (-) | 621 | WP_024425129.1 | transcriptional repressor LexA | - |
| ACLCDX_RS08870 (ACLCDX_08870) | yneA | 1772102..1772413 (+) | 312 | WP_024425130.1 | cell division suppressor protein YneA | - |
| ACLCDX_RS08875 (ACLCDX_08875) | - | 1772431..1773078 (+) | 648 | WP_122631359.1 | recombinase family protein | - |
| ACLCDX_RS08880 (ACLCDX_08880) | - | 1773148..1773378 (+) | 231 | WP_024425132.1 | DUF896 domain-containing protein | - |
Sequence
Protein
Download Length: 126 a.a. Molecular weight: 13761.43 Da Isoelectric Point: 8.5068
>NTDB_id=1094972 ACLCDX_RS08845 WP_051149980.1 1768584..1768964(+) (nucA/comI) [Bacillus safensis strain BS22LVI]
MGTLFGGFGEKQAAKGADRYDHVVQFPKERYPETGSHIQEAIRKGHSDVCTIDRNGADARRQESLKGIPTKPGFDRDEWP
MAVCLEGGKGASVQYVSPSDNRGAGSWVGHQISGFPDGKRILFIVK
MGTLFGGFGEKQAAKGADRYDHVVQFPKERYPETGSHIQEAIRKGHSDVCTIDRNGADARRQESLKGIPTKPGFDRDEWP
MAVCLEGGKGASVQYVSPSDNRGAGSWVGHQISGFPDGKRILFIVK
Nucleotide
Download Length: 381 bp
>NTDB_id=1094972 ACLCDX_RS08845 WP_051149980.1 1768584..1768964(+) (nucA/comI) [Bacillus safensis strain BS22LVI]
ATGGGCACGTTGTTTGGCGGATTTGGAGAGAAGCAGGCAGCAAAAGGGGCTGATCGATATGATCATGTCGTTCAATTTCC
AAAGGAAAGGTACCCTGAAACAGGCAGTCATATTCAAGAAGCCATTCGAAAAGGGCATTCAGATGTGTGTACCATTGACC
GAAATGGAGCAGATGCCCGCAGGCAAGAATCATTAAAAGGAATTCCGACAAAACCTGGCTTTGACCGGGATGAATGGCCA
ATGGCGGTTTGTCTTGAGGGAGGAAAAGGCGCAAGCGTTCAATATGTCAGTCCATCTGATAATAGGGGAGCAGGCTCATG
GGTCGGGCATCAAATCAGCGGGTTTCCTGATGGGAAAAGAATATTATTCATTGTGAAATAA
ATGGGCACGTTGTTTGGCGGATTTGGAGAGAAGCAGGCAGCAAAAGGGGCTGATCGATATGATCATGTCGTTCAATTTCC
AAAGGAAAGGTACCCTGAAACAGGCAGTCATATTCAAGAAGCCATTCGAAAAGGGCATTCAGATGTGTGTACCATTGACC
GAAATGGAGCAGATGCCCGCAGGCAAGAATCATTAAAAGGAATTCCGACAAAACCTGGCTTTGACCGGGATGAATGGCCA
ATGGCGGTTTGTCTTGAGGGAGGAAAAGGCGCAAGCGTTCAATATGTCAGTCCATCTGATAATAGGGGAGCAGGCTCATG
GGTCGGGCATCAAATCAGCGGGTTTCCTGATGGGAAAAGAATATTATTCATTGTGAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| nucA/comI | Bacillus subtilis subsp. subtilis str. 168 |
57.983 |
94.444 |
0.548 |