Detailed information NTG0109337

Bioinformatically predicted

Overview

• Name: radA
• Type: Machinery gene
• Locus tag: ACGHWZ_RS09450
• Genome accession: NZ_AP031431
• Coordinates: 1910587..1911960 (+)
• Length: 457 a.a.
• NCBI ID: WP_054339558.1
• Uniprot ID: -
• Organism: Flavonifractor plautii strain i30-0019-1B1
• Function: homologous recombination (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	1907145..1924858	1910587..1911960	within	0

Gene organization within MGE regions

Location: 1907145..1924858

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACGHWZ_RS09425 (I3000191B1_18620)	-	1907145..1907846 (-)	702	WP_390593050.1	ABC transporter ATP-binding protein	-
ACGHWZ_RS09430 (I3000191B1_18630)	-	1908010..1908606 (-)	597	WP_024724095.1	manganese catalase family protein	-
ACGHWZ_RS09435 (I3000191B1_18640)	-	1908607..1909065 (-)	459	WP_334265743.1	spore coat protein CotJB	-
ACGHWZ_RS09440 (I3000191B1_18650)	-	1909252..1909710 (-)	459	WP_242864973.1	YhcH/YjgK/YiaL family protein	-
ACGHWZ_RS09445 (I3000191B1_18660)	-	1909838..1910590 (+)	753	WP_044940205.1	N-acetylmuramoyl-L-alanine amidase	-
ACGHWZ_RS09450 (I3000191B1_18670)	radA	1910587..1911960 (+)	1374	WP_054339558.1	DNA repair protein RadA	Machinery gene
ACGHWZ_RS09455 (I3000191B1_18680)	-	1912294..1912512 (-)	219	WP_369847124.1	helix-turn-helix domain-containing protein	-
ACGHWZ_RS09460 (I3000191B1_18690)	-	1912696..1912920 (+)	225	WP_007488969.1	hypothetical protein	-
ACGHWZ_RS09465 (I3000191B1_18700)	-	1913662..1914645 (+)	984	WP_369847121.1	hypothetical protein	-
ACGHWZ_RS09470 (I3000191B1_18710)	-	1914738..1915049 (+)	312	WP_288859042.1	hypothetical protein	-
ACGHWZ_RS09475	-	1915224..1915748 (+)	525	WP_007489507.1	tyrosine-type recombinase/integrase	-
ACGHWZ_RS09480 (I3000191B1_18730)	-	1915957..1916175 (-)	219	WP_024724091.1	helix-turn-helix domain-containing protein	-
ACGHWZ_RS09485 (I3000191B1_18740)	-	1916374..1916598 (+)	225	WP_007488969.1	hypothetical protein	-
ACGHWZ_RS09490 (I3000191B1_18750)	-	1917340..1918323 (+)	984	WP_390593057.1	hypothetical protein	-
ACGHWZ_RS09495 (I3000191B1_18760)	-	1918416..1918727 (+)	312	WP_390593059.1	hypothetical protein	-
ACGHWZ_RS09500 (I3000191B1_18770)	-	1918902..1919426 (+)	525	WP_007489507.1	tyrosine-type recombinase/integrase	-
ACGHWZ_RS09505 (I3000191B1_18780)	-	1919526..1920554 (+)	1029	WP_009256857.1	tyrosine recombinase XerC	-
ACGHWZ_RS09510 (I3000191B1_18790)	-	1920594..1922195 (-)	1602	WP_257590793.1	hypothetical protein	-
ACGHWZ_RS09515 (I3000191B1_18800)	-	1922244..1922777 (-)	534	WP_196033410.1	amidase domain-containing protein	-
ACGHWZ_RS09520 (I3000191B1_18810)	ligA	1922858..1924858 (-)	2001	WP_369847117.1	NAD-dependent DNA ligase LigA	-

Sequence

Protein

• Length: 457 a.a.
• Molecular weight: 49071.54 Da
• Isoelectric Point: 5.8607

>NTDB_id=109337 ACGHWZ_RS09450 WP_054339558.1 1910587..1911960(+) (radA) [Flavonifractor plautii strain i30-0019-1B1]
MKAKTLFYCTECGNETPKWSGQCPACRAWNTLVERPTEPKKRSAAAASVAGGGLRGTGNRPRPMREVETTHELRFETGMN
ELDRVLGGGAVKGSLVLVGGAPGIGKSTLMLQICDNLCRFASVLYVSGEESERQIKLRAERLHVRGEGMYLLAETNLEDV
LESVNELKPDVLIVDSIQTLYNGDLTTAPGSVGQVKDCTMALMQLAKGQGITVFVIGHVNKEGSIAGPKVLEHMVDCVLY
FEGEQQNSYRILRAAKNRFGATNEIGVFEMEDSGLSEVPNPSEMLLSGRPQDTPGTCVTCVMEGVRPVLAEVQALLAPTS
FNVPRRTANGFDFNRANLLLAVLEKRGGLMVSSCDAYINVIGGLFLDEPAADLAMIVALASSFRDKPVPGDLAAIGEVGL
TGELRSVNALGQRLSEVRRLGFTKCLIPARTGGKLDAPDGLQLIPVRNIREALAALL

Nucleotide

• Length: 1374 bp

>NTDB_id=109337 ACGHWZ_RS09450 WP_054339558.1 1910587..1911960(+) (radA) [Flavonifractor plautii strain i30-0019-1B1]
ATGAAAGCAAAAACACTGTTTTATTGTACCGAGTGTGGAAATGAAACCCCAAAGTGGTCCGGCCAATGTCCCGCCTGCCG
GGCATGGAATACCCTTGTGGAGCGGCCGACAGAGCCGAAAAAGAGGAGTGCGGCCGCCGCCTCTGTCGCTGGGGGCGGCC
TGCGGGGAACCGGCAACCGGCCCAGGCCCATGCGCGAGGTGGAAACCACCCACGAGCTCCGCTTTGAAACCGGGATGAAT
GAGCTGGACCGGGTGCTGGGCGGGGGAGCGGTGAAGGGCTCTCTGGTGCTGGTGGGGGGTGCCCCCGGCATTGGCAAGTC
CACCCTGATGCTCCAGATCTGCGACAACCTGTGCCGTTTTGCCTCTGTGCTCTATGTCTCCGGGGAGGAGTCGGAGCGGC
AGATCAAGCTGCGGGCGGAGCGGCTCCATGTCCGTGGAGAGGGAATGTACCTTCTGGCTGAGACCAACCTAGAGGATGTG
CTGGAGTCGGTCAACGAGCTGAAGCCAGACGTGCTAATTGTGGACTCCATCCAGACCCTCTACAACGGGGATCTGACCAC
CGCTCCCGGCAGCGTAGGACAGGTAAAGGACTGTACTATGGCGCTGATGCAGTTGGCGAAGGGGCAGGGGATCACCGTCT
TTGTCATCGGACACGTCAATAAGGAGGGGTCTATCGCGGGCCCCAAGGTGCTGGAGCACATGGTGGACTGCGTGCTCTAT
TTCGAAGGTGAGCAGCAGAACTCCTACCGCATTCTGCGCGCGGCAAAGAACCGTTTCGGCGCCACCAATGAGATCGGCGT
CTTTGAGATGGAGGACTCCGGCCTGAGTGAAGTGCCCAATCCCTCGGAGATGCTGCTCTCGGGACGGCCTCAGGACACCC
CCGGCACCTGCGTCACCTGCGTCATGGAGGGAGTGCGGCCTGTTTTGGCCGAGGTACAGGCCCTGCTGGCGCCCACCAGC
TTCAATGTACCGCGCAGGACCGCCAACGGCTTCGACTTCAACCGGGCGAATCTGCTGCTGGCTGTTCTGGAAAAGCGGGG
CGGACTGATGGTCAGTTCCTGTGACGCCTATATTAACGTCATCGGCGGCTTGTTTTTGGACGAGCCCGCCGCCGACCTGG
CCATGATCGTCGCACTGGCTTCCAGCTTCCGGGACAAGCCCGTGCCTGGAGATCTGGCCGCCATCGGCGAGGTTGGCCTG
ACCGGAGAGCTGCGCTCAGTCAATGCGTTGGGCCAGCGGTTGAGCGAGGTGCGCCGTCTGGGGTTCACAAAGTGCCTGAT
CCCAGCCCGTACCGGCGGAAAGCTGGACGCCCCGGATGGCCTGCAGCTCATTCCGGTCCGCAACATCCGTGAGGCGCTGG
CCGCGCTTTTGTAG

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (366-454)

• AAA domain (AAA_25) (72-223)

• Rubredoxin metal binding domain (Zn_ribbon_LapB) (7-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
radA	Bacillus subtilis subsp. subtilis str. 168	52.954	100	0.53
radA	Streptococcus pneumoniae Rx1	50	99.781	0.499
radA	Streptococcus pneumoniae D39	50	99.781	0.499
radA	Streptococcus pneumoniae R6	50	99.781	0.499
radA	Streptococcus pneumoniae TIGR4	50	99.781	0.499
radA	Streptococcus mitis NCTC 12261	50	99.781	0.499
radA	Streptococcus mitis SK321	50	99.781	0.499