Detailed information NTG1092539

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACKAX6_RS09640
• Genome accession: NZ_CP179215
• Coordinates: 1967885..1968928 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain YNSA7
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1962885..1973928

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACKAX6_RS09610 (ACKAX6_09610)	-	1963306..1964562 (-)	1257	WP_078065149.1	aminopeptidase	-
ACKAX6_RS09615 (ACKAX6_09615)	-	1964565..1964765 (-)	201	WP_000180460.1	DUF1128 family protein	-
ACKAX6_RS09620 (ACKAX6_09620)	-	1964912..1965376 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
ACKAX6_RS09625 (ACKAX6_09625)	-	1965383..1965658 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
ACKAX6_RS09630 (ACKAX6_09630)	-	1965936..1967153 (+)	1218	WP_000037087.1	YihY/virulence factor BrkB family protein	-
ACKAX6_RS09635 (ACKAX6_09635)	vraR	1967266..1967895 (-)	630	WP_000153526.1	two-component system response regulator VraR	Regulator
ACKAX6_RS09640 (ACKAX6_09640)	vraS	1967885..1968928 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
ACKAX6_RS09645 (ACKAX6_09645)	liaF	1968925..1969626 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
ACKAX6_RS09650 (ACKAX6_09650)	-	1969641..1970027 (-)	387	WP_111058724.1	hypothetical protein	-
ACKAX6_RS09655 (ACKAX6_09655)	map	1970244..1971002 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
ACKAX6_RS09660 (ACKAX6_09660)	-	1971531..1972517 (+)	987	WP_000999708.1	FUSC family protein	-
ACKAX6_RS09665 (ACKAX6_09665)	-	1972950..1973363 (-)	414	WP_025174552.1	hypothetical protein	-
ACKAX6_RS09670 (ACKAX6_09670)	-	1973392..1973502 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1092539 ACKAX6_RS09640 WP_001017131.1 1967885..1968928(-) (vraS) [Staphylococcus aureus strain YNSA7]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1092539 ACKAX6_RS09640 WP_001017131.1 1967885..1968928(-) (vraS) [Staphylococcus aureus strain YNSA7]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGTATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAACGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGATCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1