Detailed information NTG0109110

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: HW09_RS15435
• Genome accession: NZ_CP008857
• Coordinates: 3355552..3358116 (-)
• Length: 854 a.a.
• NCBI ID: WP_003094682.1
• Uniprot ID: A0A0H2ZHB4
• Organism: Pseudomonas aeruginosa strain F30658
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3350552..3363116

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HW09_RS15410 (HW09_15620)	mobH	3351513..3353435 (+)	1923	WP_003454525.1	MobH family relaxase	-
HW09_RS15415 (HW09_15625)	-	3353432..3354733 (+)	1302	WP_003454526.1	site-specific integrase	-
HW09_RS15435 (HW09_15645)	clpC	3355552..3358116 (-)	2565	WP_003094682.1	ATP-dependent chaperone ClpB	Regulator
HW09_RS15440 (HW09_15650)	pgeF	3358272..3359000 (-)	729	WP_003102588.1	peptidoglycan editing factor PgeF	-
HW09_RS15445 (HW09_15655)	rluD	3358997..3359959 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
HW09_RS15450 (HW09_15660)	-	3360105..3361130 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
HW09_RS15455 (HW09_15665)	-	3361287..3361532 (+)	246	WP_003102591.1	PP0621 family protein	-
HW09_RS15460 (HW09_15670)	pilS	3361522..3363114 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator

Sequence

Protein

• Length: 854 a.a.
• Molecular weight: 95005.65 Da
• Isoelectric Point: 5.1331

>NTDB_id=109110 HW09_RS15435 WP_003094682.1 3355552..3358116(-) (clpC) [Pseudomonas aeruginosa strain F30658]
MRIDRLTSKLQLALSDAQSLAVGHDHPAIEPVHLLSALLEQQGGSIKPLLMQVGFDIAALRSGLNKELDALPKIQSPTGD
VNLSQDLARLLNQADRLAQQKGDQFISSELVLLAAMDENTRLGKLLLGQGVSRKALENAVANLRGGEAVNDPNVEESRQA
LDKYTVDMTKRAEEGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPDGLKDKRLLAL
DMGALIAGAKFRGEFEERLKAVLNELGKQEGRVILFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPSEEDTIAILRGLKERYEVHHGVSITDGAIIAAAKLSHRYITDRQLPDKAIDLIDEAASR
IRMEIDSKPEELDRLDRRLIQLKIEREALKKEDDEATRKRLAKLEEDIVKLEREYADLEEIWKSEKAEVQGSAQIQQKIE
QAKQEMEAARRKGDLESMARIQYQTIPDLERSLQMVDQHGKTENQLLRNKVTDEEIAEVVSKWTGIPVSKMLEGEREKLL
RMEQELHRRVIGQDEAVVAVSNAVRRSRAGLADPNRPSGSFLFLGPTGVGKTELCKALAEFLFDTEEALVRIDMSEFMEK
HSVARLIGAPPGYVGFEEGGYLTEAIRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRLTDSHGRTVDFRNTVVVMTSNL
GSAQIQELAGDREAQRAAVMDAVNAHFRPEFINRIDEVVVFEPLAREQIAGIAEIQLGRLRKRLAERELSLELSQEALDK
LIAVGFDPVYGARPLKRAIQRWIENPLAQLILAGKFAPGASISAKVEGDEIVFA

Nucleotide

• Length: 2565 bp

>NTDB_id=109110 HW09_RS15435 WP_003094682.1 3355552..3358116(-) (clpC) [Pseudomonas aeruginosa strain F30658]
ATGCGAATAGACCGTTTGACCAGCAAGCTGCAACTGGCGCTCTCCGACGCCCAGTCCCTGGCCGTTGGCCATGACCATCC
GGCCATCGAGCCGGTGCACCTGCTTTCCGCCCTGCTCGAGCAGCAAGGCGGTTCGATCAAGCCCCTGCTGATGCAGGTCG
GCTTCGATATCGCCGCCCTGCGCAGCGGCCTCAACAAAGAACTCGACGCGCTGCCGAAGATCCAGAGCCCGACCGGCGAC
GTGAACCTGTCCCAGGATCTCGCACGCCTGCTCAACCAGGCTGACCGCCTGGCCCAGCAGAAGGGCGACCAGTTCATCTC
CAGCGAGCTGGTATTGCTGGCCGCGATGGACGAGAACACCAGGCTCGGCAAGCTGCTGCTCGGCCAGGGCGTGTCGCGCA
AGGCGCTGGAGAATGCCGTGGCCAACCTGCGTGGCGGCGAAGCGGTGAACGACCCGAACGTCGAGGAGTCGCGCCAGGCG
CTGGACAAGTACACCGTCGACATGACCAAGCGCGCCGAGGAAGGCAAGCTCGACCCGGTGATCGGTCGCGACGACGAGAT
CCGCCGGACCATCCAGGTCCTGCAGCGGCGGACCAAGAACAACCCGGTGCTGATCGGCGAACCCGGCGTCGGCAAGACCG
CCATCGTCGAGGGCCTGGCCCAGCGCATCATCAACGGCGAAGTGCCGGACGGCCTCAAGGACAAGCGCCTGCTGGCCCTG
GACATGGGGGCGCTGATCGCCGGTGCCAAGTTCCGCGGCGAGTTCGAGGAACGCCTGAAGGCGGTCCTCAACGAACTGGG
CAAGCAGGAAGGCCGGGTCATCCTGTTCATCGACGAACTGCACACCATGGTCGGCGCCGGCAAGGCGGAAGGTGCCATGG
ACGCCGGCAACATGCTCAAGCCGGCTCTGGCGCGCGGCGAGCTGCACTGCGTCGGTGCTACTACCCTCGACGAGTATCGC
CAGTACATCGAGAAGGATGCCGCGCTGGAGCGCCGCTTCCAGAAGGTGCTGGTGGACGAACCGAGCGAGGAAGACACCAT
CGCCATCCTCCGTGGTCTCAAGGAACGCTATGAAGTGCACCACGGGGTGAGCATCACCGACGGCGCGATCATCGCCGCGG
CCAAGCTGTCGCACCGCTACATCACCGATCGGCAACTGCCGGACAAGGCCATCGACCTGATCGACGAGGCCGCCAGCCGC
ATCCGCATGGAGATCGACTCCAAGCCGGAGGAACTGGATCGTCTCGACCGTCGCCTGATCCAGCTGAAGATCGAGCGTGA
GGCGCTGAAGAAGGAAGACGACGAAGCCACCAGGAAGCGCCTGGCCAAGCTGGAGGAGGACATCGTCAAGCTCGAGCGCG
AATACGCCGACCTCGAGGAGATCTGGAAGTCCGAGAAGGCCGAGGTGCAGGGCTCGGCGCAGATCCAGCAGAAGATCGAG
CAGGCCAAGCAGGAGATGGAGGCGGCGCGGCGCAAGGGCGACCTCGAGAGCATGGCGCGCATCCAGTACCAGACCATCCC
GGACCTGGAACGCAGCCTGCAGATGGTCGACCAGCACGGCAAGACCGAGAACCAGTTGCTGCGCAACAAGGTGACCGACG
AGGAAATCGCCGAAGTGGTTTCCAAGTGGACCGGTATCCCGGTGTCGAAGATGCTCGAGGGCGAGCGCGAGAAGCTGCTG
CGCATGGAGCAGGAGCTGCATCGGCGAGTGATCGGCCAGGACGAGGCGGTAGTCGCCGTGTCCAACGCCGTGCGCCGTTC
GCGCGCCGGCCTCGCCGATCCGAACCGGCCGAGCGGCTCGTTCCTCTTCCTCGGCCCGACCGGGGTGGGCAAGACCGAGT
TGTGCAAGGCGCTGGCCGAGTTCCTCTTCGATACCGAGGAGGCGCTGGTGCGGATCGATATGTCCGAGTTCATGGAGAAA
CACTCGGTGGCCCGCCTGATCGGCGCGCCTCCGGGCTACGTCGGCTTCGAGGAAGGCGGCTACCTGACCGAGGCGATCCG
CCGCAAGCCTTACTCGGTGGTGCTGCTGGACGAGGTGGAGAAGGCCCATCCGGATGTATTCAACATTCTCCTCCAGGTGC
TCGAGGACGGACGCCTGACCGACAGTCACGGGCGTACGGTGGACTTCCGCAACACCGTGGTGGTGATGACCTCCAACCTC
GGTTCGGCACAGATCCAGGAGCTGGCCGGCGACCGCGAGGCGCAACGTGCCGCAGTGATGGACGCGGTCAATGCGCACTT
CCGTCCGGAATTCATCAACCGGATCGACGAAGTGGTGGTATTCGAGCCGCTGGCTCGCGAGCAGATCGCCGGCATCGCCG
AGATCCAGCTCGGTCGCCTGCGCAAGCGCCTGGCCGAGCGCGAGCTGAGCCTGGAACTGAGCCAGGAGGCGCTGGACAAG
CTGATCGCCGTCGGCTTCGACCCGGTCTATGGCGCACGCCCGCTGAAGCGGGCCATCCAGCGCTGGATCGAGAACCCGCT
GGCGCAACTGATCCTGGCCGGCAAATTCGCGCCGGGTGCCAGTATCTCGGCGAAGGTGGAAGGCGACGAGATCGTCTTCG
CCTGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-444)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (764-842)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-758)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-334)

3D structure

• AlphaFold DB: A0A0H2ZHB4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	48.391	100	0.493
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.417	100	0.436