Detailed information NTG1090974

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: ACLZ8F_RS04445
• Genome accession: NZ_CP178723
• Coordinates: 964776..965822 (+)
• Length: 348 a.a.
• NCBI ID: WP_002486322.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain 42.1-1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 959776..970822

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLZ8F_RS04420 (ACLZ8F_04420)	isaB	960917..961453 (+)	537	WP_001830372.1	immunodominant staphylococcal antigen IsaB family protein	-
ACLZ8F_RS04425 (ACLZ8F_04425)	-	961604..962590 (-)	987	WP_002457091.1	FUSC family protein	-
ACLZ8F_RS04430 (ACLZ8F_04430)	map	962764..963519 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
ACLZ8F_RS04435 (ACLZ8F_04435)	-	963677..964063 (+)	387	WP_001830382.1	hypothetical protein	-
ACLZ8F_RS04440 (ACLZ8F_04440)	liaF	964078..964779 (+)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
ACLZ8F_RS04445 (ACLZ8F_04445)	vraS	964776..965822 (+)	1047	WP_002486322.1	sensor histidine kinase	Regulator
ACLZ8F_RS04450 (ACLZ8F_04450)	vraR	965812..966441 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
ACLZ8F_RS04455 (ACLZ8F_04455)	-	966498..967676 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
ACLZ8F_RS04460 (ACLZ8F_04460)	-	968083..968367 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
ACLZ8F_RS04465 (ACLZ8F_04465)	-	968375..968839 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
ACLZ8F_RS04470 (ACLZ8F_04470)	-	968980..969195 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
ACLZ8F_RS04475 (ACLZ8F_04475)	-	969197..970438 (+)	1242	WP_002457094.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40039.46 Da
• Isoelectric Point: 5.8512

>NTDB_id=1090974 ACLZ8F_RS04445 WP_002486322.1 964776..965822(+) (vraS) [Staphylococcus epidermidis strain 42.1-1]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVSIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=1090974 ACLZ8F_RS04445 WP_002486322.1 964776..965822(+) (vraS) [Staphylococcus epidermidis strain 42.1-1]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAGTATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.733	98.851	0.917