Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACL6EO_RS05890 Genome accession   NZ_CP178718
Coordinates   1139440..1140096 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain SY1154     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1134440..1145096
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACL6EO_RS05865 (ACL6EO_05865) oppF 1134972..1135889 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ACL6EO_RS05870 (ACL6EO_05870) - 1135996..1137183 (+) 1188 WP_022553557.1 putative glycoside hydrolase -
  ACL6EO_RS05875 (ACL6EO_05875) - 1137301..1137879 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  ACL6EO_RS05880 (ACL6EO_05880) spx 1138058..1138453 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  ACL6EO_RS05885 (ACL6EO_05885) - 1138508..1139164 (-) 657 WP_413385205.1 TerC family protein -
  ACL6EO_RS05890 (ACL6EO_05890) mecA 1139440..1140096 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  ACL6EO_RS05895 (ACL6EO_05895) - 1140248..1141408 (+) 1161 WP_413385208.1 competence protein CoiA family protein -
  ACL6EO_RS05900 (ACL6EO_05900) pepF 1141636..1143465 (+) 1830 WP_094296111.1 oligoendopeptidase F Regulator
  ACL6EO_RS05905 (ACL6EO_05905) - 1143503..1143670 (-) 168 WP_003155026.1 hypothetical protein -
  ACL6EO_RS05910 (ACL6EO_05910) spxH 1143956..1144858 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=1090911 ACL6EO_RS05890 WP_003155032.1 1139440..1140096(+) (mecA) [Bacillus velezensis strain SY1154]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1090911 ACL6EO_RS05890 WP_003155032.1 1139440..1140096(+) (mecA) [Bacillus velezensis strain SY1154]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCCAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment