Detailed information NTG0109072

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ACAM21_RS09590
• Genome accession: NZ_AP031395
• Coordinates: 1840588..1841625 (-)
• Length: 345 a.a.
• NCBI ID: WP_050200217.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16P29
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1835588..1846625

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM21_RS09565 (SPNE16P29_18710)	-	1836389..1837720 (-)	1332	WP_000390046.1	hemolysin family protein	-
ACAM21_RS09570 (SPNE16P29_18720)	endA	1837949..1838773 (-)	825	WP_001036779.1	DNA-entry nuclease EndA	Machinery gene
ACAM21_RS09575 (SPNE16P29_18730)	-	1838812..1839000 (-)	189	WP_050218344.1	DNA-directed RNA polymerase subunit beta	-
ACAM21_RS09580 (SPNE16P29_18740)	murA	1838993..1840276 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ACAM21_RS09585 (SPNE16P29_18750)	-	1840300..1840530 (-)	231	WP_000250384.1	DUF1146 family protein	-
ACAM21_RS09590 (SPNE16P29_18760)	sepM	1840588..1841625 (-)	1038	WP_050200217.1	SepM family pheromone-processing serine protease	Regulator
ACAM21_RS09595 (SPNE16P29_18770)	coaD	1841609..1842097 (-)	489	WP_001280742.1	pantetheine-phosphate adenylyltransferase	-
ACAM21_RS09600 (SPNE16P29_18780)	rsmD	1842087..1842626 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ACAM21_RS09605 (SPNE16P29_18790)	asnA	1842691..1843683 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
ACAM21_RS09610 (SPNE16P29_18800)	-	1843796..1844479 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
ACAM21_RS09615 (SPNE16P29_18810)	-	1844535..1845275 (-)	741	WP_000152674.1	RNA methyltransferase	-
ACAM21_RS09620 (SPNE16P29_18820)	-	1845309..1845587 (+)	279	WP_001174613.1	acylphosphatase	-
ACAM21_RS09625 (SPNE16P29_18830)	yidC	1845665..1846591 (+)	927	WP_000835944.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37549.63 Da
• Isoelectric Point: 5.0724

>NTDB_id=109072 ACAM21_RS09590 WP_050200217.1 1840588..1841625(-) (sepM) [Streptococcus pneumoniae strain 16P29]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
IIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=109072 ACAM21_RS09590 WP_050200217.1 1840588..1841625(-) (sepM) [Streptococcus pneumoniae strain 16P29]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ATAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591