Detailed information NTG0108992

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ACAM23_RS09580
• Genome accession: NZ_AP031394
• Coordinates: 1839610..1840647 (-)
• Length: 345 a.a.
• NCBI ID: WP_050200217.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16P28
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1834610..1845647

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM23_RS09555 (SPNE16P28_18660)	-	1835411..1836742 (-)	1332	WP_000390046.1	hemolysin family protein	-
ACAM23_RS09560 (SPNE16P28_18670)	endA	1836971..1837795 (-)	825	WP_001036779.1	DNA-entry nuclease EndA	Machinery gene
ACAM23_RS09565 (SPNE16P28_18680)	-	1837834..1838022 (-)	189	WP_050218344.1	DNA-directed RNA polymerase subunit beta	-
ACAM23_RS09570 (SPNE16P28_18690)	murA	1838015..1839298 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ACAM23_RS09575 (SPNE16P28_18700)	-	1839322..1839552 (-)	231	WP_000250384.1	DUF1146 family protein	-
ACAM23_RS09580 (SPNE16P28_18710)	sepM	1839610..1840647 (-)	1038	WP_050200217.1	SepM family pheromone-processing serine protease	Regulator
ACAM23_RS09585 (SPNE16P28_18720)	coaD	1840631..1841119 (-)	489	WP_001280742.1	pantetheine-phosphate adenylyltransferase	-
ACAM23_RS09590 (SPNE16P28_18730)	rsmD	1841109..1841648 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ACAM23_RS09595 (SPNE16P28_18740)	asnA	1841713..1842705 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
ACAM23_RS09600 (SPNE16P28_18750)	-	1842818..1843501 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
ACAM23_RS09605 (SPNE16P28_18760)	-	1843557..1844297 (-)	741	WP_000152674.1	RNA methyltransferase	-
ACAM23_RS09610 (SPNE16P28_18770)	-	1844331..1844609 (+)	279	WP_001174613.1	acylphosphatase	-
ACAM23_RS09615 (SPNE16P28_18780)	yidC	1844687..1845613 (+)	927	WP_000835944.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37549.63 Da
• Isoelectric Point: 5.0724

>NTDB_id=108992 ACAM23_RS09580 WP_050200217.1 1839610..1840647(-) (sepM) [Streptococcus pneumoniae strain 16P28]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
IIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=108992 ACAM23_RS09580 WP_050200217.1 1839610..1840647(-) (sepM) [Streptococcus pneumoniae strain 16P28]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ATAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591