Detailed information NTG0108976

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: HW10_RS02460
• Genome accession: NZ_CP008856
• Coordinates: 520144..522942 (+)
• Length: 932 a.a.
• NCBI ID: WP_003160891.1
• Uniprot ID: -
• Organism: Pseudomonas aeruginosa strain F23197
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 515144..527942

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HW10_RS02430 (HW10_10990)	dbpA	515359..516735 (-)	1377	WP_003118837.1	ATP-dependent RNA helicase DbpA	-
HW10_RS02435 (HW10_10985)	-	517083..517292 (+)	210	WP_003084710.1	cold-shock protein	-
HW10_RS02440 (HW10_10980)	-	517443..517967 (+)	525	WP_003099931.1	ATP-dependent zinc protease	-
HW10_RS02445 (HW10_10975)	-	517961..518335 (-)	375	WP_033936306.1	YkvA family protein	-
HW10_RS02450 (HW10_10970)	mdtD	518337..519770 (-)	1434	WP_003084717.1	multidrug transporter subunit MdtD	-
HW10_RS02460 (HW10_10965)	clpC	520144..522942 (+)	2799	WP_003160891.1	AAA family protein disaggregase ClpG	Regulator
HW10_RS02465 (HW10_10960)	-	523044..523622 (+)	579	WP_003084725.1	DUF2780 domain-containing protein	-
HW10_RS02470 (HW10_10955)	-	523937..524824 (-)	888	WP_003099939.1	acyltransferase	-
HW10_RS02475 (HW10_10950)	-	524967..525476 (+)	510	WP_003084733.1	ATP-dependent zinc protease	-
HW10_RS02480 (HW10_10945)	creB	525561..526250 (+)	690	WP_003113268.1	two-component system response regulator CreB	-
HW10_RS02485 (HW10_10940)	creC	526250..527674 (+)	1425	WP_033936307.1	two-component system sensor histidine kinase CreC	-

Sequence

Protein

• Length: 932 a.a.
• Molecular weight: 103467.98 Da
• Isoelectric Point: 6.8717

>NTDB_id=108976 HW10_RS02460 WP_003160891.1 520144..522942(+) (clpC) [Pseudomonas aeruginosa strain F23197]
MAQELCAICHERPAVARVSLVQNGQRRELALCELHYRQLMRQQRMRSPLESLFGGGSPFDEIFSGFGEQSPVTPVRAREP
EAVDIAEYFSKQTTEYLQRAAQVAAEFGKREVDTEHLLYALADADVVQAVLKQFGLSPADLKQYIEANAVRGASKGEASE
DMTISPRVKSALQHAFALSRELGHSYVGPEHLLLGLAAVPDSFAGTLLKKYGLTEQALRQKAVKVVGKGAEDGRVDGPSN
TPQLDKFSRDLTRLAREGKLDPVIGRSKEVETTIEVLARRKKNNPVLIGEPGVGKTAIVEGLAQRMVQGEVPEVLRDKRL
VELNINAMVAGAKYRGEFEERLKQVMDELQAAQSEIILFIDEVHTIVGAGQGGGEGGLDVANVLKPAMARGEMNLIGATT
LNEYQKYIEKDAALERRFQPVFVPEPTVEQTISILRGLRDKLEGHHKVTIRDEAFVAAAELSDRYIGNRFLPDKAIDLID
QAAARVRIASTSRPAEIQELEAELAQLKREQDYAASRKWYDEAKVFEKRIQERKEHLEQITERWQQTQGSKTEEVRVEDI
AEIISRLTGIPVTELTAEEREKLLQMEERLHQRVIGQQEAITAVSDAVRLARAGLRQGSRPIATFLFLGPTGVGKTELAK
ALAEVVFGDEDAMIRIDMSEYMERHAVSRLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHADVNNILLQVFDD
GRLTDGKGRVVDFTNTIIIATSNLGSELIMKNAQAGEFAQPPEKLKRELMTTLRGHFRPEFLNRLDEVIVFESLSKAQIE
DIVRLQLERVKRAAHAQDIYLHIDDSLVGHLAEEAYQPEFGARELKRQIRQQLETRLATAMLKGEVKEGETVTFFYDAKD
GVGYRKGAAPKPAARKKSGAGETPRGRATAARKPAAKKGAAAKGKADKPKTK

Nucleotide

• Length: 2799 bp

>NTDB_id=108976 HW10_RS02460 WP_003160891.1 520144..522942(+) (clpC) [Pseudomonas aeruginosa strain F23197]
ATGGCCCAGGAACTTTGCGCTATCTGCCACGAACGTCCCGCCGTCGCCCGCGTCAGCCTGGTACAGAACGGCCAGCGCCG
CGAACTCGCCCTCTGCGAACTGCACTACCGCCAGTTGATGCGCCAGCAGCGCATGCGCTCGCCGCTGGAGTCGCTGTTCG
GCGGCGGCAGCCCGTTCGACGAGATCTTCTCCGGCTTCGGCGAGCAGAGCCCGGTCACCCCGGTGCGCGCCCGCGAGCCG
GAGGCGGTGGACATCGCCGAGTACTTCAGCAAGCAGACCACCGAGTACCTGCAACGCGCCGCGCAGGTCGCCGCCGAATT
CGGCAAGCGCGAAGTGGATACCGAGCACCTGCTCTACGCCCTGGCCGACGCCGACGTGGTGCAGGCGGTGCTCAAGCAGT
TCGGCCTGTCGCCGGCCGACCTCAAGCAGTACATCGAGGCCAACGCCGTGCGCGGCGCCAGCAAGGGCGAGGCGAGCGAG
GACATGACCATCTCGCCGCGGGTGAAGAGCGCCTTGCAGCATGCCTTCGCCCTGTCCCGCGAACTCGGCCACAGCTATGT
CGGCCCCGAGCACCTGTTGCTCGGCCTGGCGGCGGTGCCGGACAGCTTCGCCGGGACGCTCCTGAAGAAGTACGGCCTGA
CCGAGCAGGCGCTACGGCAGAAAGCGGTCAAGGTGGTCGGCAAGGGCGCCGAGGACGGCCGCGTGGACGGCCCGAGCAAC
ACTCCGCAACTGGACAAGTTCAGCCGCGACCTGACCCGGCTGGCCCGCGAAGGCAAGCTCGATCCGGTGATCGGCCGCTC
GAAGGAAGTCGAGACCACCATCGAGGTTCTCGCCCGGCGCAAGAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCG
GCAAGACCGCCATCGTCGAAGGCCTGGCCCAGCGCATGGTCCAGGGCGAGGTGCCGGAGGTGCTGCGCGACAAGCGCCTG
GTCGAACTGAACATCAACGCCATGGTCGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAACGCCTCAAGCAGGTGATGGA
CGAACTGCAGGCGGCGCAGAGCGAGATCATCCTGTTCATCGACGAGGTGCACACCATCGTTGGTGCCGGCCAGGGCGGCG
GCGAAGGCGGGCTGGACGTGGCCAACGTGCTGAAGCCGGCGATGGCGCGCGGCGAGATGAACCTGATCGGCGCCACCACC
CTCAACGAGTACCAGAAGTACATCGAGAAGGACGCCGCGCTGGAGCGGCGCTTCCAGCCGGTGTTCGTCCCCGAGCCGAC
GGTGGAGCAGACCATCTCCATCCTCCGTGGCCTGCGCGACAAGCTCGAAGGCCACCACAAGGTGACCATCCGCGACGAGG
CCTTCGTCGCCGCCGCCGAGCTGTCCGATCGCTACATCGGCAACCGCTTCCTGCCGGACAAGGCCATCGACCTGATCGAC
CAGGCCGCCGCCCGCGTGCGCATCGCCAGCACCTCGCGGCCGGCCGAGATCCAGGAACTGGAGGCCGAGCTGGCGCAGCT
CAAGCGCGAGCAGGACTACGCCGCCAGCCGCAAGTGGTACGACGAGGCGAAGGTCTTCGAGAAACGCATCCAGGAACGCA
AGGAACACCTCGAGCAGATCACCGAGCGCTGGCAGCAGACCCAGGGGTCGAAGACCGAGGAGGTGCGGGTCGAGGACATC
GCCGAGATCATCTCCAGGCTCACCGGCATCCCGGTCACCGAACTGACCGCCGAGGAGCGCGAGAAGCTCCTGCAGATGGA
AGAGCGCCTGCACCAGCGGGTGATCGGCCAGCAGGAAGCGATCACCGCGGTCAGCGACGCCGTGCGCCTGGCCCGCGCCG
GGCTGCGCCAGGGCAGCCGGCCGATCGCCACCTTCCTGTTCCTCGGCCCGACCGGGGTGGGCAAGACCGAGCTGGCCAAG
GCCCTGGCCGAGGTGGTGTTCGGCGACGAAGACGCGATGATCCGCATCGACATGAGCGAATACATGGAGCGCCACGCGGT
GTCCCGGCTGATCGGTGCGCCGCCGGGCTACGTCGGCTACGACGAGGGCGGCCAGCTCACCGAGCGGGTGCGCCGGCGGC
CGTACAGCGTGATCCTGCTCGATGAGATCGAGAAGGCCCACGCCGACGTCAACAACATCCTCCTGCAGGTGTTCGACGAC
GGCCGCCTGACCGACGGCAAGGGGCGCGTGGTGGACTTCACCAATACCATCATCATCGCCACCAGCAACCTAGGCTCCGA
GCTGATCATGAAGAACGCCCAGGCCGGCGAGTTCGCCCAGCCGCCGGAGAAGCTCAAGCGCGAACTGATGACTACCCTGC
GCGGACATTTCCGCCCGGAATTCCTCAACCGCCTCGACGAGGTGATCGTCTTCGAGTCGCTGAGCAAGGCGCAGATCGAG
GACATCGTGCGCCTGCAACTGGAGCGGGTGAAGCGCGCCGCGCACGCTCAGGACATCTACCTGCACATCGACGACAGCCT
GGTCGGCCACCTCGCCGAAGAGGCCTACCAGCCGGAGTTCGGCGCCCGCGAGCTGAAGCGGCAGATCCGCCAGCAACTGG
AGACGCGCCTGGCCACGGCGATGCTCAAGGGCGAGGTGAAGGAGGGCGAGACGGTCACCTTCTTCTACGACGCCAAGGAC
GGCGTCGGCTACCGCAAGGGCGCCGCGCCGAAGCCGGCGGCACGCAAGAAGTCCGGCGCCGGCGAGACGCCCAGGGGCCG
CGCGACGGCGGCGAGGAAGCCGGCGGCGAAGAAAGGCGCCGCCGCCAAGGGCAAGGCCGACAAGCCGAAGACCAAGTGA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (100-147)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (175-226)

• AAA domain (Cdc48 subfamily) (AAA_2) (620-788)

• ATPase family associated with various cellular activities (AAA) (AAA) (286-419)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (794-873)

• AAA lid domain (AAA_lid_9) (427-524)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	50.374	86.052	0.433
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	45.113	85.622	0.386
clpC	Streptococcus thermophilus LMD-9	42.805	88.734	0.38
clpC	Streptococcus thermophilus LMG 18311	42.563	88.734	0.378
clpC	Streptococcus mutans UA159	41.383	88.412	0.366