Detailed information    

insolico Bioinformatically predicted

Overview

Name   spo0A   Type   Regulator
Locus tag   ACLNGX_RS11750 Genome accession   NZ_CP178374
Coordinates   2498181..2498981 (-) Length   266 a.a.
NCBI ID   WP_003153177.1    Uniprot ID   I2C7K5
Organism   Bacillus velezensis strain 2023     
Function   activation and repression of comK; repression of rok; repression of abrB (predicted from homology)   
Competence regulation

Genomic Context

Location: 2493181..2503981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLNGX_RS11720 (ACLNGX_11720) - 2493730..2494362 (+) 633 WP_071391633.1 helix-turn-helix domain-containing protein -
  ACLNGX_RS11725 (ACLNGX_11725) - 2494653..2494790 (+) 138 WP_014470646.1 hypothetical protein -
  ACLNGX_RS11730 (ACLNGX_11730) - 2494884..2496002 (+) 1119 WP_198863797.1 NADH-dependent flavin oxidoreductase -
  ACLNGX_RS11735 (ACLNGX_11735) - 2496129..2496341 (+) 213 WP_003153183.1 spore germination protein -
  ACLNGX_RS11740 (ACLNGX_11740) - 2496468..2496680 (+) 213 WP_003153181.1 spore germination protein -
  ACLNGX_RS11745 (ACLNGX_11745) alr 2496856..2498037 (+) 1182 WP_102421903.1 alanine racemase -
  ACLNGX_RS11750 (ACLNGX_11750) spo0A 2498181..2498981 (-) 801 WP_003153177.1 sporulation transcription factor Spo0A Regulator
  ACLNGX_RS11755 (ACLNGX_11755) spoIVB 2499262..2500542 (-) 1281 WP_198863798.1 SpoIVB peptidase -
  ACLNGX_RS11760 (ACLNGX_11760) recN 2500706..2502436 (-) 1731 WP_202735625.1 DNA repair protein RecN Machinery gene
  ACLNGX_RS11765 (ACLNGX_11765) ahrC 2502468..2502917 (-) 450 WP_003153173.1 transcriptional regulator AhrC/ArgR -
  ACLNGX_RS11770 (ACLNGX_11770) - 2503012..2503857 (-) 846 WP_071391630.1 TlyA family RNA methyltransferase -

Sequence

Protein


Download         Length: 266 a.a.        Molecular weight: 29630.11 Da        Isoelectric Point: 6.1630

>NTDB_id=1089152 ACLNGX_RS11750 WP_003153177.1 2498181..2498981(-) (spo0A) [Bacillus velezensis strain 2023]
MEKIKVCVADDNRELVSLLSEYIEGQDDMEVIGVAYNGQECLSLFKDKNPDVLVLDIIMPHLDGLAVLERLRESELEKQP
NVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLVGHIRQVSGNVSSVTHRAPSAQSSIIRSQPEPKRKNLDASITSII
HEIGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVS
MTKAKPTNSEFIAMVADKLRLEHKAS

Nucleotide


Download         Length: 801 bp        

>NTDB_id=1089152 ACLNGX_RS11750 WP_003153177.1 2498181..2498981(-) (spo0A) [Bacillus velezensis strain 2023]
GTGGAGAAAATTAAAGTTTGTGTTGCTGATGATAATCGAGAGCTTGTAAGCCTGTTGAGTGAATATATAGAGGGACAGGA
TGATATGGAAGTGATCGGCGTTGCTTATAACGGACAGGAATGTCTTTCTTTGTTTAAAGATAAGAATCCCGATGTGCTCG
TTTTAGACATTATCATGCCGCATCTGGACGGACTTGCGGTTTTGGAGCGTCTGCGGGAATCAGAGCTCGAGAAGCAGCCG
AACGTCATCATGCTGACGGCATTCGGTCAGGAAGACGTTACGAAAAAAGCCGTCGATTTAGGCGCGTCCTATTTCATCCT
GAAGCCGTTTGATATGGAAAACCTTGTCGGCCATATCCGCCAGGTAAGCGGAAATGTCAGCAGTGTCACACACCGTGCGC
CGTCCGCGCAAAGCAGCATTATCCGCAGCCAGCCGGAGCCGAAGCGGAAAAATCTCGATGCCAGCATTACAAGCATTATC
CATGAGATCGGTGTGCCTGCCCATATCAAAGGCTATCTTTATTTGCGTGAAGCCATTTCCATGGTGTATAACGATATTGA
ACTCCTCGGCAGCATCACAAAAGTCCTTTATCCCGACATCGCCAAAAAATTCAACACGACCGCAAGCCGTGTAGAACGGG
CCATCCGCCACGCCATTGAAGTCGCATGGAGCAGGGGAAATATTGATTCCATTTCTTCACTGTTCGGATATACGGTAAGC
ATGACAAAAGCAAAACCAACCAATTCAGAGTTCATCGCGATGGTTGCTGACAAGCTGAGATTGGAGCATAAAGCTTCGTA
A

Domains

Predicted by InterproScan.

Sporulation initiation factor Spo0A C terminal (Spo0A_C)

(156-259)

Response regulator receiver domain (Response_reg)

(6-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C7K5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  spo0A Bacillus subtilis subsp. subtilis str. 168

96.629

100

0.97

Multiple sequence alignment