Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ACLNGX_RS06010 Genome accession   NZ_CP178374
Coordinates   1146219..1146875 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain 2023     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1141219..1151875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLNGX_RS05985 (ACLNGX_05985) oppF 1141748..1142665 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  ACLNGX_RS05990 (ACLNGX_05990) - 1142772..1143959 (+) 1188 WP_166706486.1 putative glycoside hydrolase -
  ACLNGX_RS05995 (ACLNGX_05995) - 1144077..1144655 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  ACLNGX_RS06000 (ACLNGX_06000) spx 1144834..1145229 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  ACLNGX_RS06005 (ACLNGX_06005) - 1145287..1145943 (-) 657 WP_003155033.1 TerC family protein -
  ACLNGX_RS06010 (ACLNGX_06010) mecA 1146219..1146875 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  ACLNGX_RS06015 (ACLNGX_06015) - 1147026..1148186 (+) 1161 WP_146283635.1 competence protein CoiA family protein -
  ACLNGX_RS06020 (ACLNGX_06020) pepF 1148414..1150243 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  ACLNGX_RS06025 (ACLNGX_06025) - 1150281..1150448 (-) 168 WP_003155026.1 hypothetical protein -
  ACLNGX_RS06030 (ACLNGX_06030) spxH 1150734..1151636 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=1089139 ACLNGX_RS06010 WP_003155032.1 1146219..1146875(+) (mecA) [Bacillus velezensis strain 2023]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1089139 ACLNGX_RS06010 WP_003155032.1 1146219..1146875(+) (mecA) [Bacillus velezensis strain 2023]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCTTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment