Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   ACFCT9_RS09880 Genome accession   NZ_CP178241
Coordinates   2043966..2045315 (+) Length   449 a.a.
NCBI ID   WP_412518990.1    Uniprot ID   -
Organism   Staphylococcus simulans strain PFJB-50N     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2037251..2048282 2043966..2045315 within 0


Gene organization within MGE regions


Location: 2037251..2048282
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFCT9_RS09850 - 2037251..2038030 (-) 780 WP_213017850.1 hypothetical protein -
  ACFCT9_RS09855 - 2038116..2040047 (-) 1932 WP_204194915.1 ATP-dependent DNA helicase -
  ACFCT9_RS09860 - 2040167..2041159 (+) 993 WP_310797022.1 hypothetical protein -
  ACFCT9_RS09865 ssb 2041342..2041635 (+) 294 WP_412518985.1 cassette chromosome ssDNA-binding protein -
  ACFCT9_RS09870 cch1 2041635..2043428 (+) 1794 WP_412518987.1 cassette chromosome replicative helicase -
  ACFCT9_RS09875 - 2043497..2043775 (+) 279 WP_412518988.1 hypothetical protein -
  ACFCT9_RS09880 ccrA 2043966..2045315 (+) 1350 WP_412518990.1 cassette chromosome recombinase CcrA Machinery gene
  ACFCT9_RS09885 ccrB 2045336..2046964 (+) 1629 WP_248313711.1 cassette chromosome recombinase CcrB Machinery gene
  ACFCT9_RS09890 - 2047000..2047287 (-) 288 WP_412518992.1 hypothetical protein -
  ACFCT9_RS09895 - 2047841..2048179 (+) 339 WP_053464901.1 SAUGI family uracil-DNA glycosylase inhibitor -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51922.74 Da        Isoelectric Point: 10.1301

>NTDB_id=1088624 ACFCT9_RS09880 WP_412518990.1 2043966..2045315(+) (ccrA) [Staphylococcus simulans strain PFJB-50N]
MKQAIGYLRQSTTKQQSLAAQKQAIKTLAEKHNIQHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKAKQGKMITTHAPFGYQYH
NGTFTIDTVKAPTIKAVFSYYLQGYGYKKIAQYLEADEKFINRKPYQVRNIIMNPNYCGRVINQYGQYDNMCPSIVSTSI
YEQAQAIRSQKQLKRTSSANQLKQKIKCPYCGSTLTNITIRKKHRTLRYYVCPQNMNASRFVCEFKGINAQSLEASVLAT
CQDFFQNQQLYSKINHTIQQRLKKQRMHDTSNTLTQEKLIENLAQGKIDVETFREQSQSINLQNKPIQAISDIRIKASLQ
KVIQKSFTLNMLNPYIDEVRITKNKALVGIYFKNEPLNIVNQTSQSSIV

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1088624 ACFCT9_RS09880 WP_412518990.1 2043966..2045315(+) (ccrA) [Staphylococcus simulans strain PFJB-50N]
ATGAAACAAGCAATAGGTTACTTACGACAGAGCACTACAAAGCAACAATCCCTAGCAGCACAGAAACAAGCCATCAAGAC
ATTAGCTGAAAAACACAATATTCAACACATCACATTTTATAGCGATAAGCAATCAGGACGCACTGATAAGCGGAATGGTT
ATCAACAAATTACTGAACTGATTCAACAAGGACAATGTGACGTACTATGTTGCTATCGTCTGAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAACTCATGAAATTATGTCAAAAATACCATGTTCATATCTTAAGCGTTCATGATGGCTATTTTGA
TATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAACTAGAATCCGATAATATAGGCGAAC
AAGTCAAAAATGGAATCAAAGAAAAAGCGAAACAAGGTAAAATGATTACAACACATGCACCCTTTGGGTATCAATATCAT
AATGGTACTTTCACGATAGACACAGTAAAAGCACCAACAATAAAAGCTGTATTCAGTTATTATCTTCAAGGCTATGGTTA
TAAAAAAATTGCACAGTACTTAGAAGCTGACGAGAAATTCATCAATCGTAAACCCTATCAAGTACGTAATATTATCATGA
ACCCCAATTATTGTGGTCGAGTCATTAATCAATACGGGCAATATGACAACATGTGTCCTTCTATTGTTTCGACAAGTATA
TATGAACAAGCTCAAGCGATACGATCACAAAAGCAACTCAAACGGACATCATCAGCTAATCAACTCAAACAAAAAATCAA
ATGTCCTTATTGTGGTTCAACGTTGACTAATATAACCATTAGAAAAAAGCACCGTACATTACGTTATTATGTCTGTCCAC
AAAATATGAATGCATCTCGTTTTGTCTGTGAATTCAAAGGAATCAACGCACAATCATTAGAAGCGAGTGTCTTAGCTACA
TGTCAAGACTTCTTTCAAAATCAACAGTTGTATTCAAAAATCAACCATACAATTCAACAACGACTCAAAAAACAAAGGAT
GCATGATACTAGTAACACATTAACTCAGGAAAAGCTTATTGAAAATTTAGCACAAGGAAAAATTGATGTAGAAACATTCA
GAGAACAGTCCCAATCAATTAATCTACAGAATAAACCTATACAAGCAATAAGTGATATTCGTATAAAAGCATCACTACAA
AAGGTTATACAGAAAAGTTTCACGTTAAACATGCTGAATCCCTATATTGATGAAGTTCGCATTACAAAAAACAAAGCCCT
TGTTGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGTTTAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(170-250)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

84.855

100

0.849
  ccrA Staphylococcus aureus N315

73.497

100

0.735

Multiple sequence alignment