Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   ACLFAM_RS05475 Genome accession   NZ_CP178226
Coordinates   1092661..1093689 (-) Length   342 a.a.
NCBI ID   WP_003132657.1    Uniprot ID   S6FVM6
Organism   Lactococcus lactis strain L-WY410     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1087661..1098689
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLFAM_RS05450 (ACLFAM_05450) - 1087946..1088443 (-) 498 WP_039116485.1 nitroreductase family protein -
  ACLFAM_RS05455 (ACLFAM_05455) - 1088430..1088639 (-) 210 WP_003132661.1 hypothetical protein -
  ACLFAM_RS05460 (ACLFAM_05460) - 1088636..1089361 (-) 726 WP_017865174.1 radical SAM protein -
  ACLFAM_RS05465 (ACLFAM_05465) - 1089457..1091580 (-) 2124 WP_039116487.1 MFS transporter -
  ACLFAM_RS05470 (ACLFAM_05470) - 1091683..1092540 (-) 858 WP_039116490.1 transcriptional regulator -
  ACLFAM_RS05475 (ACLFAM_05475) sepM 1092661..1093689 (-) 1029 WP_003132657.1 SepM family pheromone-processing serine protease Regulator
  ACLFAM_RS05480 (ACLFAM_05480) coaD 1093676..1094173 (-) 498 WP_010906348.1 pantetheine-phosphate adenylyltransferase -
  ACLFAM_RS05485 (ACLFAM_05485) rsmD 1094221..1094760 (-) 540 WP_050558566.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  ACLFAM_RS05490 (ACLFAM_05490) - 1094931..1096151 (-) 1221 WP_039116754.1 MDR family MFS transporter -
  ACLFAM_RS05495 (ACLFAM_05495) lmrP 1096234..1097460 (-) 1227 WP_039116491.1 multidrug efflux MFS transporter LmrP -

Sequence

Protein


Download         Length: 342 a.a.        Molecular weight: 37349.96 Da        Isoelectric Point: 9.9183

>NTDB_id=1088562 ACLFAM_RS05475 WP_003132657.1 1092661..1093689(-) (sepM) [Lactococcus lactis strain L-WY410]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide


Download         Length: 1029 bp        

>NTDB_id=1088562 ACLFAM_RS05475 WP_003132657.1 1092661..1093689(-) (sepM) [Lactococcus lactis strain L-WY410]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGCGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(134-194)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(227-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FVM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.696

100

0.491

Multiple sequence alignment