Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   SP5448_RS05640 Genome accession   NZ_CP008776
Coordinates   1098512..1098988 (-) Length   158 a.a.
NCBI ID   WP_010922230.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 5448     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1093512..1103988
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP5448_RS05625 (SP5448_05855) fbp54 1094325..1095977 (+) 1653 WP_010922232.1 Rqc2 family fibronectin-binding protein Fbp54 -
  SP5448_RS05630 (SP5448_05860) - 1096036..1097283 (-) 1248 WP_010922231.1 tetratricopeptide repeat protein -
  SP5448_RS05635 (SP5448_05865) - 1097273..1098454 (-) 1182 WP_002990002.1 AI-2E family transporter -
  SP5448_RS05640 (SP5448_05870) mutX 1098512..1098988 (-) 477 WP_010922230.1 8-oxo-dGTP diphosphatase Machinery gene
  SP5448_RS05645 (SP5448_05875) rfbB 1099209..1100249 (-) 1041 WP_011285494.1 dTDP-glucose 4,6-dehydratase -
  SP5448_RS05650 (SP5448_05880) - 1100493..1101086 (-) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  SP5448_RS05655 (SP5448_05885) rfbA 1101086..1101955 (-) 870 WP_010922195.1 glucose-1-phosphate thymidylyltransferase RfbA -
  SP5448_RS05660 (SP5448_05890) - 1102013..1103119 (-) 1107 WP_011285493.1 FAD-dependent oxidoreductase -
  SP5448_RS05665 (SP5448_05895) - 1103159..1103947 (-) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18452.64 Da        Isoelectric Point: 4.3268

>NTDB_id=108617 SP5448_RS05640 WP_010922230.1 1098512..1098988(-) (mutX) [Streptococcus pyogenes strain 5448]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRSFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=108617 SP5448_RS05640 WP_010922230.1 1098512..1098988(-) (mutX) [Streptococcus pyogenes strain 5448]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTTCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

69.62

100

0.696

Multiple sequence alignment