Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   ACJVC4_RS01645 Genome accession   NZ_CP177179
Coordinates   314256..315785 (+) Length   509 a.a.
NCBI ID   WP_002889963.1    Uniprot ID   J7SI89
Organism   Streptococcus salivarius strain MRD-NRLLH     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 309256..320785
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJVC4_RS01620 - 309792..310463 (-) 672 WP_002889958.1 potassium channel family protein -
  ACJVC4_RS01625 - 310503..311797 (-) 1295 Protein_280 TrkH family potassium uptake protein -
  ACJVC4_RS01630 rsmG 311866..312579 (-) 714 WP_002889960.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  ACJVC4_RS01635 - 312878..313414 (+) 537 WP_002889961.1 DUF177 domain-containing protein -
  ACJVC4_RS01640 covR 313570..314259 (+) 690 WP_002883757.1 response regulator transcription factor Regulator
  ACJVC4_RS01645 covS 314256..315785 (+) 1530 WP_002889963.1 HAMP domain-containing histidine kinase Regulator
  ACJVC4_RS01650 nrdR 315907..316386 (+) 480 WP_002883820.1 transcriptional regulator NrdR -
  ACJVC4_RS01655 - 316383..317558 (+) 1176 WP_002889965.1 DnaD domain protein -
  ACJVC4_RS01660 dnaI 317562..318464 (+) 903 WP_002889966.1 primosomal protein DnaI -
  ACJVC4_RS01665 der 318570..319880 (+) 1311 WP_037597430.1 ribosome biogenesis GTPase Der -
  ACJVC4_RS01670 - 319945..320574 (+) 630 WP_037597433.1 hypothetical protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58068.44 Da        Isoelectric Point: 5.1853

>NTDB_id=1085785 ACJVC4_RS01645 WP_002889963.1 314256..315785(+) (covS) [Streptococcus salivarius strain MRD-NRLLH]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSMFTLVVVFSANTLLLQRERQNVNNTISKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLFSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLIFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERPAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALEDEMLVQVQDNGEGISKEDIEHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=1085785 ACJVC4_RS01645 WP_002889963.1 314256..315785(+) (covS) [Streptococcus salivarius strain MRD-NRLLH]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGATGTTCACTCTGGTTGTTGTTTTCTCGGCCAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAA
ATAACACAATTTCGAAAGTTGTTACTTATATCGAAAAGGACTGGGATTCTGATGAAGAGTTGAGTCCAGAACCGCTTTTA
GCGGCCCTTTATTCGCCTAAAAATATCTATGCATCAATCATTAATGGTGTGCTTTCTGAAAAGCACTCTTTGGATGGTCA
AGTTGCAATTTCTAATAAATTATTTTCTAACCAATCTGTTTTTGTTTATGACAAAAAGGGAACGTTTATCTTTACTTCTG
AGGAAAACACAGACTCTCCTCCAGGCATGTCTGAAGTAAACAAACTGAAGTCAGTGTCCTATAAAGGAAAGCGTGGTTTC
TTACTACAAGTTCCAATTTACGGTAAGGATAAAAAGACCATCGTTGGTTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTGAAAGAGCGTTTGATTTTCTTATTGATTTTCCTAGAAGTGGGGATGACGGTTCTAGTTATCGCAGCAACTG
TGGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATCACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGTATGATGGATAAAAT
CCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTGCGTACGCCGATTGCGGTTATTAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAGGAAAGTCTTGAGGCTGCCAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGACATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCATAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGTAACTTCCGCGTCTTGCACGAAGACTACCAATTCTATCTCA
ATGATTTCGAGAGCTCAGAGCGCCCTGCACAGATTTACAGCCAACACTTTGAACAGGCGATTACGATTTTGATTGATAAT
GCGGTCAAGTATTCTCCTGTTAACAAGGAAATCCAGGTTACAATTAAGGCTCTGGAAGATGAAATGTTGGTGCAAGTGCA
AGATAATGGTGAAGGGATCTCTAAAGAAGATATTGAGCATATCTTTGAGCGCTTCTACCGTTCAGATAAGGCACGTAACC
GTACGACAACGCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTACCAAATTGTGGAAGCTTATCGCTGCCGTATCGAT
GTTAGTTCTGAACTCGGTGTTGGAACACGTTTCGACCTTTACATTCCATTTGCGGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

ArlS sensor domain (ArlS_N)

(43-191)

HAMP domain (HAMP)

(217-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J7SI89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

99.607

100

0.996

Multiple sequence alignment