Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilL-C   Type   Machinery gene
Locus tag   ACLB6K_RS12100 Genome accession   NZ_CP177167
Coordinates   2499058..2502135 (+) Length   1025 a.a.
NCBI ID   WP_042790758.1    Uniprot ID   -
Organism   Microcystis aeruginosa FACHB-524     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2494058..2507135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLB6K_RS12060 (ACLB6K_12055) - 2494280..2495101 (-) 822 WP_123230323.1 inositol monophosphatase family protein -
  ACLB6K_RS12065 (ACLB6K_12060) - 2495116..2495484 (-) 369 WP_002737677.1 2Fe-2S iron-sulfur cluster-binding protein -
  ACLB6K_RS12070 (ACLB6K_12065) - 2495581..2495721 (-) 141 WP_002737679.1 hypothetical protein -
  ACLB6K_RS12075 (ACLB6K_12070) - 2496055..2496825 (+) 771 WP_123230322.1 FkbM family methyltransferase -
  ACLB6K_RS12080 (ACLB6K_12075) - 2496808..2497035 (-) 228 WP_238142283.1 hypothetical protein -
  ACLB6K_RS12085 (ACLB6K_12080) - 2497087..2498028 (-) 942 WP_069474128.1 homogentisate phytyltransferase -
  ACLB6K_RS12095 (ACLB6K_12090) - 2498289..2498951 (-) 663 WP_002735180.1 class I SAM-dependent methyltransferase -
  ACLB6K_RS12100 (ACLB6K_12095) pilL-C 2499058..2502135 (+) 3078 WP_042790758.1 hybrid sensor histidine kinase/response regulator Machinery gene
  ACLB6K_RS12105 (ACLB6K_12100) miaA 2502809..2503744 (+) 936 WP_036396432.1 tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA -
  ACLB6K_RS12110 (ACLB6K_12105) - 2503686..2505091 (-) 1406 Protein_2398 DUF2079 domain-containing protein -
  ACLB6K_RS12115 (ACLB6K_12110) - 2505104..2505961 (-) 858 WP_123230320.1 amino acid ABC transporter substrate-binding protein -
  ACLB6K_RS12120 (ACLB6K_12115) - 2505998..2507017 (-) 1020 WP_123230319.1 AI-2E family transporter -

Sequence

Protein


Download         Length: 1025 a.a.        Molecular weight: 113038.22 Da        Isoelectric Point: 4.3127

>NTDB_id=1085760 ACLB6K_RS12100 WP_042790758.1 2499058..2502135(+) (pilL-C) [Microcystis aeruginosa FACHB-524]
MMKPDWDHFFNEDLEQLLESLEDKDTDGDETLDELSFLFEQTSPPAARYGASLDQTLSFLPLEPELAELFSDSINWEETA
TNDLHSTRGTAAKSEAEDWDDLESLLLENATVQDSEAIITISNPNFYDSLEDLEAFLEKPTPPAQSPLPDIFESLEVFLW
ESTAGEPLAATEPLQRLESLEIATESSPEPEFKDLEKLLEETNPPVGLNNLRPLVGKAFEQTMRVPIKQLDNLSNLIGEL
VVKRNHLEQEQDRLRLFLDNLLTCVQNLSDVGVRMQDLYERSLLEGALLASRNAGGAIGYDGVQGKNQGNSTMTGELDAL
EIDRFTDFHLLSQEMIELIVRVRESASDLQFVVDETDQVTRSLRQATTQLQEGMTKSRMVPFSQTADHLPRAIHDISLKL
HKQAKLKVEGGGVLIDQMILENLNSPMIHLVNNAITHGIESPEERLAKGKPVHGTISVRAFLQGNQTVITVSDDGAGIDV
NLVKLKAIEKGLISDREAQNLSTQEVYEILFHPGFSTKDQADDFAGRGVGLDVVRTSLIDVRGTITIDSVLGQGTTFTLR
LPLTLSICKALCCVSNHARIGFSMDGVEDVRDFRARDIQMDREGRRCVFWQNTLLPFQPLSDLLSYNRQLSRGSFYTGKQ
GEDSFAIVILRGGNNLLAVQVDQVIGEQEIVIKQIEGPIPKTAGIAGATVLGDGTVMPVGDVLELIDIASGRLRIDNGGL
WRQSVPPVDVEISQKSEAMVLIVDDSITVRELLSLSFSKTGYRVEQARDGQEAWEKLRGGLPCDIVFCDIEMPRMNGLEL
LSNLQKYPRLATIPVALLTSRGSERHRQVAAKLGASGYFTKPYTEIDLLSAAERMIAGEVLLANSIKATSNQLSSSDTTI
IDSDPANLLAQSSPLVLIVDDSLIVREMLAISLVKAGYRIEQAQDGLEAWEKLQAGLACDLILCDIEMPRLNGLELLSRL
QEDEQLQGIPVAIIAYQGTQKMQHLAAAKGAKGYFVKPYIEDVLLSAAQRLIAGEVLIQKESSVD

Nucleotide


Download         Length: 3078 bp        

>NTDB_id=1085760 ACLB6K_RS12100 WP_042790758.1 2499058..2502135(+) (pilL-C) [Microcystis aeruginosa FACHB-524]
ATGATGAAACCCGACTGGGATCATTTCTTTAACGAAGATCTCGAACAGTTGTTAGAGAGTTTAGAAGACAAAGACACCGA
CGGTGACGAGACCCTAGACGAACTTAGCTTTTTATTTGAGCAGACTTCCCCGCCAGCGGCGAGGTATGGGGCTTCTCTTG
ACCAAACCCTGTCTTTCTTGCCCTTAGAACCGGAATTAGCAGAACTTTTTAGCGATAGCATCAATTGGGAAGAAACCGCC
ACTAATGATCTTCATTCTACCCGTGGGACTGCTGCCAAGTCAGAAGCCGAAGATTGGGATGATCTGGAATCGCTGCTGCT
AGAAAATGCAACAGTCCAGGACTCAGAGGCAATTATAACCATCAGCAACCCGAATTTTTACGACAGCCTCGAAGACTTAG
AAGCTTTTCTGGAAAAACCCACTCCACCAGCGCAATCGCCACTGCCGGACATCTTTGAATCCCTAGAGGTCTTCCTCTGG
GAATCCACAGCAGGGGAGCCTCTGGCCGCGACAGAACCTCTCCAACGGTTAGAATCACTGGAAATTGCCACGGAAAGCTC
CCCAGAGCCTGAATTCAAGGATTTAGAAAAACTCCTCGAAGAAACCAATCCACCGGTCGGGTTAAATAACCTGCGTCCCC
TTGTTGGTAAAGCTTTTGAACAGACGATGCGGGTGCCGATCAAACAATTGGACAACCTCAGCAATCTGATCGGGGAACTG
GTGGTTAAACGCAATCACCTTGAACAGGAACAGGATCGCCTGCGTCTCTTTTTAGATAATTTGCTAACCTGCGTCCAAAA
TCTCAGCGATGTGGGCGTTCGGATGCAGGATCTCTATGAAAGAAGCCTCCTAGAAGGGGCTTTACTGGCTAGTCGCAATG
CTGGTGGTGCCATCGGTTACGATGGAGTTCAGGGAAAAAATCAGGGCAATTCGACTATGACTGGGGAACTAGATGCCCTA
GAGATCGACCGTTTTACCGATTTCCACTTATTATCCCAAGAGATGATCGAATTGATCGTGCGAGTGCGAGAATCGGCCTC
TGATCTTCAATTTGTCGTCGATGAAACCGATCAGGTGACGCGCAGTCTGCGACAGGCTACCACCCAACTACAGGAAGGGA
TGACCAAATCGCGCATGGTTCCCTTTAGTCAAACTGCCGATCATCTACCCCGGGCAATTCACGATATTTCCCTGAAACTG
CACAAACAAGCCAAATTAAAAGTGGAAGGAGGGGGTGTTCTCATCGATCAGATGATCCTCGAAAATCTCAATAGTCCCAT
GATCCATCTGGTCAACAATGCGATCACCCACGGCATTGAATCACCCGAAGAACGCCTGGCCAAAGGCAAACCTGTCCACG
GTACGATCTCGGTTCGGGCATTCCTACAGGGCAATCAAACCGTGATCACCGTTAGTGATGATGGGGCCGGTATTGATGTT
AATCTGGTTAAACTTAAGGCGATCGAAAAAGGCCTGATCAGCGATCGGGAAGCTCAAAACCTCAGTACCCAAGAAGTCTA
TGAAATTCTTTTTCATCCCGGTTTTAGTACCAAAGATCAGGCCGATGATTTTGCCGGTCGTGGGGTGGGTTTAGATGTGG
TGCGTACCAGTTTAATCGATGTGCGCGGGACGATTACTATTGACTCGGTACTGGGCCAAGGAACCACTTTTACCCTCCGT
TTACCCCTAACCCTGAGTATCTGTAAGGCCCTCTGTTGTGTTAGTAATCATGCTCGCATCGGTTTCTCCATGGACGGAGT
GGAAGATGTGAGGGATTTCCGGGCCAGGGATATCCAAATGGATCGGGAGGGACGGCGCTGCGTTTTCTGGCAAAACACTT
TACTACCTTTCCAACCCTTGAGCGATTTGCTTTCCTACAATCGACAACTTAGTCGCGGTAGTTTTTACACCGGCAAACAG
GGGGAAGACTCTTTTGCGATCGTGATCCTGCGCGGTGGTAATAATCTCCTCGCGGTACAGGTGGATCAAGTGATCGGGGA
ACAGGAGATCGTGATCAAACAGATTGAAGGACCGATTCCGAAAACGGCTGGGATTGCTGGGGCGACGGTTTTAGGCGATG
GTACGGTGATGCCCGTCGGCGATGTGTTAGAGTTGATCGACATCGCCAGCGGTCGTCTGCGTATCGATAACGGTGGTCTT
TGGCGCCAATCCGTACCGCCTGTAGATGTGGAAATTAGCCAAAAATCCGAGGCTATGGTTCTGATTGTCGATGATTCGAT
TACTGTTCGGGAATTGCTCTCTTTAAGCTTTAGTAAAACTGGTTATCGTGTGGAACAAGCTCGGGATGGTCAAGAAGCTT
GGGAAAAATTACGCGGTGGTTTGCCCTGTGATATCGTTTTTTGTGATATCGAGATGCCCCGCATGAATGGCCTGGAATTA
CTGTCTAATTTGCAAAAATACCCCCGATTAGCGACGATTCCCGTGGCTTTGTTGACTTCCCGAGGCTCGGAACGTCATCG
TCAGGTGGCGGCGAAATTAGGGGCCAGTGGTTATTTTACCAAGCCCTACACGGAAATAGATTTACTCTCGGCAGCTGAAA
GAATGATTGCGGGGGAAGTATTACTAGCTAATAGTATTAAAGCGACCTCTAATCAGCTTTCATCCTCCGATACAACGATT
ATTGATAGTGATCCCGCTAATTTGTTAGCACAATCGAGTCCTCTCGTCTTGATTGTCGATGATTCGTTAATAGTGCGGGA
AATGTTAGCGATTTCTTTGGTTAAAGCTGGTTATCGCATTGAACAGGCCCAGGACGGTTTAGAAGCATGGGAAAAATTAC
AGGCCGGATTAGCTTGTGATCTGATTCTCTGCGATATCGAAATGCCTCGCCTGAATGGGTTAGAATTACTCTCTCGTCTG
CAAGAGGATGAACAACTTCAGGGGATACCAGTGGCGATAATTGCCTACCAAGGGACGCAAAAAATGCAGCATCTTGCCGC
CGCTAAAGGGGCAAAAGGTTATTTTGTCAAGCCCTATATTGAGGATGTTTTACTTTCAGCAGCCCAACGTTTAATCGCTG
GTGAGGTATTAATCCAGAAAGAAAGTTCCGTGGATTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(427-564)

Signal transducing histidine kinase, homodimeric domain (H-kinase_dim)

(221-375)

CheW-like domain (CheW)

(570-707)

Response regulator receiver domain (Response_reg)

(740-852)

Response regulator receiver domain (Response_reg)

(896-1007)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilL-C Synechocystis sp. PCC 6803

65.517

84.878

0.556

Multiple sequence alignment