Detailed information NTG1085270

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: ACLIMH_RS20425
• Genome accession: NZ_CP177046
• Coordinates: 3953620..3954414 (-)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus thuringiensis strain MPB12
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 3948620..3959414

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLIMH_RS20405 (ACLIMH_20405)	-	3950421..3950654 (+)	234	WP_001190187.1	DUF2627 domain-containing protein	-
ACLIMH_RS20410 (ACLIMH_20410)	-	3950703..3951431 (-)	729	WP_411469660.1	glycerophosphodiester phosphodiesterase	-
ACLIMH_RS20415 (ACLIMH_20415)	-	3951482..3951628 (+)	147	WP_001247670.1	YycC family protein	-
ACLIMH_RS20420 (ACLIMH_20420)	-	3951796..3953322 (-)	1527	Protein_3963	hypothetical protein	-
ACLIMH_RS20425 (ACLIMH_20425)	spo0A	3953620..3954414 (-)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
ACLIMH_RS20430 (ACLIMH_20430)	spoIVB	3954702..3956000 (-)	1299	WP_002037056.1	SpoIVB peptidase	-
ACLIMH_RS20435 (ACLIMH_20435)	recN	3956119..3957858 (-)	1740	WP_000947757.1	DNA repair protein RecN	Machinery gene
ACLIMH_RS20440 (ACLIMH_20440)	argR	3958126..3958575 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=1085270 ACLIMH_RS20425 WP_003161566.1 3953620..3954414(-) (spo0A) [Bacillus thuringiensis strain MPB12]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=1085270 ACLIMH_RS20425 WP_003161566.1 3953620..3954414(-) (spo0A) [Bacillus thuringiensis strain MPB12]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCGAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCTGAGTTTATTGCAATGGTTGCGGATAAGTTGAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818