Detailed information NTG1083412

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: ACLINY_RS20605
• Genome accession: NZ_CP176864
• Coordinates: 3988442..3989236 (-)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus thuringiensis strain MPB19
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 3983442..3994236

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLINY_RS20585 (ACLINY_20585)	-	3985243..3985476 (+)	234	WP_001190187.1	DUF2627 domain-containing protein	-
ACLINY_RS20590 (ACLINY_20590)	-	3985525..3986253 (-)	729	WP_000172562.1	glycerophosphodiester phosphodiesterase	-
ACLINY_RS20595 (ACLINY_20595)	-	3986304..3986450 (+)	147	WP_001247671.1	YycC family protein	-
ACLINY_RS20600 (ACLINY_20600)	-	3986618..3988144 (-)	1527	WP_000218390.1	glycosyltransferase family 39 protein	-
ACLINY_RS20605 (ACLINY_20605)	spo0A	3988442..3989236 (-)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
ACLINY_RS20610 (ACLINY_20610)	spoIVB	3989524..3990822 (-)	1299	WP_002037056.1	SpoIVB peptidase	-
ACLINY_RS20615 (ACLINY_20615)	recN	3990941..3992680 (-)	1740	WP_000947757.1	DNA repair protein RecN	Machinery gene
ACLINY_RS20620 (ACLINY_20620)	argR	3992948..3993397 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=1083412 ACLINY_RS20605 WP_003161566.1 3988442..3989236(-) (spo0A) [Bacillus thuringiensis strain MPB19]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=1083412 ACLINY_RS20605 WP_003161566.1 3988442..3989236(-) (spo0A) [Bacillus thuringiensis strain MPB19]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCAAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818